ProVision: A web based platform for rapid analysis of proteomics data processed by MaxQuant

Simple item page
dc.contributor.authorGallant, Jamesen_ZA
dc.contributor.authorHeunis, Tiaanen_ZA
dc.contributor.authorSampson, Samantha Leighen_ZA
dc.contributor.authorBitter, Wilberten_ZA
dc.date.accessioned2022-04-12T12:42:44Z
dc.date.available2022-04-12T12:42:44Z
dc.date.issued2020-07
dc.description.abstractProteomics is a powerful tool for protein expression analysis and is becoming more readily available to researchers through core facilities or specialised collaborations. However, one major bottleneck for routine implementation and accessibility of this technology to the wider scientific community is the complexity of data analysis. To this end, we have created ProVision, a free open-source web-based analytics platform that allows users to analyse data from two common proteomics relative quantification workflows, namely label-free and tandem mass tag-based experiments. Furthermore, ProVision allows the freedom to interface with the data analysis pipeline while maintaining a user-friendly environment and providing default parameters for fast statistical and exploratory data analysis. Finally, multiple customisable quality control, differential expression plots as well as enrichments and protein-protein interaction prediction can be generated online in one platform. Availability and implementation: Quick start and step-by-step tutorials as well as tutorial data is fully incorporated in the web application. This application is available online at https://provision.shinyapps.io/provision/ for free use. The source code is available at https://github.com/JamesGallant/ProVision under the GPL version 3.0 license.en_ZA
dc.format.extent3 pages
dc.identifier.otherdoi: 10.1093/bioinformatics/btaa620
dc.identifier.urihttp://hdl.handle.net/10019.1/124450
dc.language.isoen_ZAen_ZA
dc.rights.holderAuthors retain copyright
dc.subjectproteomics dataen_ZA
dc.subjectanalysisen_ZA
dc.titleProVision: A web based platform for rapid analysis of proteomics data processed by MaxQuanten_ZA
dc.typeArticleen_ZA
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Gallant_Heunis_Sampson_Bitter_ ProVision _a web based platform for rapid analysis of proteomics_2020.pdf
Size:
128.81 KB
Format:
Adobe Portable Document Format
Description:
Main Article
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Research Articles (Molecular Biology and Human Genetics)