Expediting red blood cell transfusions by syringing causes significant hemolysis

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dc.contributor.advisorMurray, Adriaan Albertusen_ZA
dc.contributor.advisorLevin, Andrew I.en_ZA
dc.contributor.authorDe Villiers, Willem Lambertusen_ZA
dc.date.accessioned2017-11-02T11:40:06Zen_ZA
dc.date.accessioned2017-12-11T10:24:11Zen_ZA
dc.date.available2017-11-02T11:40:06Zen_ZA
dc.date.available2017-12-11T10:24:11Zen_ZA
dc.date.issued2017-12en_ZA
dc.descriptionDe Villiers, W.L., Murray, A.A. & Levin, A.I. 2017. Expediting red blood cell transfusions by syringing causes significant hemolysis. Transfusion, 57(11):2747-2751. https://doi.org/10.1111/trf.14283.en_za
dc.descriptionThe original publication is available at https://onlinelibrary.wiley.com/doi/10.1111/trf.14283en_ZA
dc.description.abstractINTRODUCTION: During resuscitation, medical personnel frequently need to expedite red blood cell concentrate (RBC) transfusions. RBC infusion rates are typically accelerated by increasing the diameter of, or pressure gradient over, the intravenous cannula. Increasing the proximal pressure is typically achieved by applying external pressure to the RBC bag. Alternatively, RBC contents may be aspirated into a syringe, which is then used to forcefully inject the blood into the patient. The latter may sometimes be the only option, for example when re-infusing cell saver blood where pressurizing the bag carries the risk of air embolism. In recent years at our hospital, manual syringing has been widely adopted even for expediting transfusions. Little is known about the effects of syringing or pressurization on red cell lysis.1,2 We decided to compare the effects of these techniques on RBC hemolysis using a simulated expedited transfusion model.en_ZA
dc.description.urihttps://onlinelibrary.wiley.com/doi/10.1111/trf.14283en_ZA
dc.description.versionpost print -- submitted versionen_ZA
dc.identifier.citationDe Villiers, W.L., Murray, A.A. & Levin, A.I. 2017. Expediting red blood cell transfusions by syringing causes significant hemolysis. Transfusion, 57(11):2747-2751. https://doi.org/10.1111/trf.14283.en_ZA
dc.identifier.issn1537-2995 (online)en_ZA
dc.identifier.issn0041-1132 (print)en_ZA
dc.identifier.otherdoi:10.1111/trf.14283en_ZA
dc.identifier.urihttp://hdl.handle.net/10019.1/102551en_ZA
dc.language.isoen_ZAen_ZA
dc.publisherStellenbosch Universityen_ZA
dc.subjectErythrocytes -- Transfusionen_ZA
dc.subjectHemolysis and hemolysinsen_ZA
dc.subjectBlood -- Transfusionen_ZA
dc.subjectHemoglobinen_ZA
dc.titleExpediting red blood cell transfusions by syringing causes significant hemolysisen_ZA
dc.typeArticleen_ZA
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