Evolution of bacteria in the human gut in response to changing environments: an invisible player in the game of health

Simple item page
dc.contributor.authorVenkatakrishnan, Aarushien_ZA
dc.contributor.authorHolzknecht, Zoie E.en_Za
dc.contributor.authorHolzknecht, Roben_ZA
dc.contributor.authorBowles, Dawn E.en_ZA
dc.contributor.authorKotzé, Sanet H.en_ZA
dc.contributor.authorModliszewski, Jennifer L.en_ZA
dc.contributor.authorParker, Williamen_ZA
dc.date.accessioned2023-05-04T09:42:51Zen_ZA
dc.date.available2023-05-04T09:42:51Zen_ZA
dc.date.issued2021-01en_ZA
dc.descriptionCITATION: Venkatakrishnan, A. et al. 2021. Evolution of bacteria in the human gut in response to changing environments: An invisible player in the game of health. Computational and Structural Biotechnology Journal 19(2021):7 pages. doi.10.1016/j.csbj.2021.01.007en_ZA
dc.descriptionThe original publication is available at: sciencedirect.comen_ZA
dc.description.abstractSeveral factors in Western society, including widespread use of antibiotics, chronic inflammation, and loss of complex eukaryotic symbionts such as helminths, have a dramatic impact on the ecosystem of the gut, affecting the microbiota hosted there. In addition, reductions in dietary fiber are profoundly impactful on the microbiota, causing extensive destruction of the niche space that supports the normally diverse microbial community in the gut. Abundant evidence now supports the view that, following dramatic alterations in the gut ecosystem, microorganisms undergo rapid change via Darwinian evolution. Such evolutionary change creates functionally distinct bacteria that may potentially have properties of pathogens but yet are difficult to distinguish from their benign predecessors.en_ZA
dc.description.versionPublisher’s versionen_ZA
dc.identifier.citationVenkatakrishnan, A. et al. 2021. Evolution of bacteria in the human gut in response to changing environments: An invisible player in the game of health. Computational and Structural Biotechnology Journal 19(2021):7 pages. doi.10.1016/j.csbj.2021.01.007en_ZA
dc.identifier.issn2001-0370en_ZA
dc.identifier.otherdoi.10.1016/j.csbj.2021.01.007en_ZA
dc.identifier.urihttp://hdl.handle.net/10019.1/126866en_ZA
dc.language.isoen_ZAen_ZA
dc.publisherElsevier B.V.en_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectGastrointestinal system -- Microbiologyen_ZA
dc.subjectIntestines -- Microbiologyen_ZA
dc.subjectGut healthen_ZA
dc.subjectFungus-bacterium relationshipsen_ZA
dc.titleEvolution of bacteria in the human gut in response to changing environments: an invisible player in the game of healthen_ZA
dc.typeArticleen_ZA
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
aarushi_evolution_2021.pdf
Size:
1.73 MB
Format:
Adobe Portable Document Format
Description:
download article
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Research Articles (Molecular Biology and Human Genetics)