How environmental exposures early in life might influence phenotypes of non-cummunicable diseases in Africa
Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
African Sun Media
Abstract
Chronic non-communicable diseases, such as diabetes, cancer, cardiovascular
and chronic respiratory diseases are leading causes of death and disability in the
world – accounting for over 60 per cent of the nearly 60 million deaths in 2008.4
Importantly, 80 per cent of non-communicable disease deaths occur in low- and
middle-income countries.5 Although Africa still has a high burden of infectious diseases, the non-communicable disease epidemic is rising rapidly; it is projected
that, by 2030, non-communicable diseases will account for 46 per cent of all deaths
in the region.6 For example, although diabetes was considered a rare disease in
Africa until about a century ago, it now affects up to a third of the population in
some countries; the prevalence of diabetes and hypertension will have increased by
nearly 80 per cent, and deaths from ischemic heart disease doubled between 2008
and 2030. This chapter discusses how environmental exposures early in life might
influence phenotypes of non-communicable diseases in Africa.
Description
CITATION: Mandy, M., Lule, S. A. & Nyirenda, M. J. 2020. How environmental exposures early in life might influence phenotypes of non-cummunicable diseases in Africa, in Macnab, A., Daar, A. & Pauw, C. 2020. Health in transition : translating developmental origins of health and disease science to improve future health in Africa. Stellenbosch: SUN PReSS, doi:10.18820/9781928357759/08.
The original publication is available at https://africansunmedia.store.it.si/za
The original publication is available at https://africansunmedia.store.it.si/za
Keywords
Diseases -- Africa, Phenotype
Citation
Mandy, M., Lule, S. A. & Nyirenda, M. J. 2020. How environmental exposures early in life might influence phenotypes of non-cummunicable diseases in Africa, in Macnab, A., Daar, A. & Pauw, C. 2020. Health in transition : translating developmental origins of health and disease science to improve future health in Africa. Stellenbosch: SUN PReSS, doi:10.18820/9781928357759/08.