The value of ultrasound examination of the lungs in predicting bronchopulmonary dysplasia

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dc.contributor.authorPieper C.H.
dc.contributor.authorSmith J.
dc.contributor.authorBrand E.J.
dc.date.accessioned2011-05-15T16:17:43Z
dc.date.available2011-05-15T16:17:43Z
dc.date.issued2004
dc.description.abstractBackground: Bronchopulmonary dysplasia (BPD) is one of the most serious complications of neonatal mechanical ventilation. Early diagnosis may influence treatment options such as early steroid administration. Objective: To assess the role of US of the lungs in predicting the development of BPD in infants with hyaline membrane disease (HMD) and to determine the earliest possible age at which the diagnosis of BPD could be made with certainty. Patients and methods: Consecutive premature newborn infants requiring assisted ventilation during 1997-1998 who were admitted because of HMD were studied prospectively. US of the lungs was performed within 3 days of birth and three times a week thereafter until discharge from the neonatal intensive care unit. Each patient was also clinically and radiographically evaluated for the presence or absence of BPD at day 28 of life. Lung US scans were correlated with the development of BPD. Results: Retrodiaphragmatic hyperechogenicity (RH) was initially observed in 28 of the 36 patients with HMD, but resolved completely in 24 (96%) of 25 infants who had an uncomplicated clinical course. In eight of the ten infants who developed BPD, RH persisted. Day 9 was the earliest day where persistence of abnormal RH was observed with the highest predictor values for the development of BPD. Conclusions: Lung US is a valuable technique for predicting the development of BPD. © Springer-Verlag 2003.
dc.description.versionArticle
dc.identifier.citationPediatric Radiology
dc.identifier.citation34
dc.identifier.citation3
dc.identifier.issn03010449
dc.identifier.other10.1007/s00247-003-1102-7
dc.identifier.urihttp://hdl.handle.net/10019.1/14337
dc.subjectarticle
dc.subjectassisted ventilation
dc.subjectclinical article
dc.subjectclinical feature
dc.subjectclinical observation
dc.subjectcontrolled study
dc.subjectcorrelation coefficient
dc.subjectdiagnostic accuracy
dc.subjectdiagnostic value
dc.subjectdiaphragm disease
dc.subjectearly diagnosis
dc.subjectechography
dc.subjectgestational age
dc.subjecthospital admission
dc.subjecthospital discharge
dc.subjecthuman
dc.subjecthyaline membrane disease
dc.subjectimage analysis
dc.subjectinfant
dc.subjectlung dysplasia
dc.subjectnewborn
dc.subjectnewborn intensive care
dc.subjectperinatal period
dc.subjectprediction
dc.subjectprematurity
dc.subjectpriority journal
dc.subjectprospective study
dc.subjectsensitivity and specificity
dc.subjectthorax radiography
dc.subjectAge of Onset
dc.subjectBronchopulmonary Dysplasia
dc.subjectHumans
dc.subjectHyaline Membrane Disease
dc.subjectInfant, Newborn
dc.subjectInfant, Premature
dc.subjectLung
dc.subjectPredictive Value of Tests
dc.subjectProspective Studies
dc.subjectRespiration, Artificial
dc.titleThe value of ultrasound examination of the lungs in predicting bronchopulmonary dysplasia
dc.typeArticle
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