Guidelines for the management of acute meningitis in children and adults in South Africa

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dc.contributor.authorBoyles, T. H.en_ZA
dc.contributor.authorBamford, C. M.en_ZA
dc.contributor.authorBateman, K.en_ZA
dc.contributor.authorBlumberg, L.en_ZA
dc.contributor.authorDramowski, A.en_ZA
dc.contributor.authorKarstaedt, A.en_ZA
dc.contributor.authorKorsman, S.en_ZA
dc.contributor.authorLe Roux, D. M.en_ZA
dc.contributor.authorMaartens, G.en_ZA
dc.contributor.authorMadhi, S.en_ZA
dc.contributor.authorNaidoo, R.en_ZA
dc.contributor.authorNuttall, J.en_ZA
dc.contributor.authorReubenson, G.en_ZA
dc.contributor.authorTaljaard, J.en_ZA
dc.contributor.authorThomas, J.en_ZA
dc.contributor.authorVan Zyl, G.en_ZA
dc.contributor.authorVon Gottberg, A.en_ZA
dc.contributor.authorWhitelaw, A.en_ZA
dc.contributor.authorMendelson, M.en_ZA
dc.date.accessioned2014-07-07T12:26:08Z
dc.date.available2014-07-07T12:26:08Z
dc.date.issued2013
dc.descriptionCITATION: Boyles, T. H. et al. 2013. Guidelines for the management of acute meningitis in children and adults in South Africa. Southern African Journal of Epidemiology and Infection, 28(1):5-15, doi:10.1080/10158782.2013.11441513.
dc.descriptionThe original publication is available at https://www.tandfonline.com
dc.description.abstractThis guideline provides a rational and cost-effective approach to patients with acute meningitis, which causes considerable morbidity and mortality, predominantly in children.There are many aetiologies, but a small number of bacteria and viruses account for the majority of cases. There should be a low threshold for suspecting acute meningitis, which is a medical emergency and antibiotics should not be delayed. Blood culture and cerebrospinal fluid (CSF) analysis are the most important diagnostic tests and should be performed whenever it is safe and practical. Contraindications to lumbar puncture are discussed and an algorithm is given regarding administering empiric antibiotics and antivirals, performing blood cultures, computer tomography brain scanning and cerebrospinal fluid analysis, depending on the clinical features and availability of resources. Administration of steroids is not recommended. Guidelines are provided for definitive therapy whenever a causative organism is identified. When no organism is identified, treatment and further investigation should be guided by laboratory results and clinical response. An approach to this process is outlined in a second algorithm. The epidemiology of resistance to common pathogens is described and advice given regarding special groups, including those with recurrent meningitis or base-of-skull fractures. Advice regarding infection control, post-exposure prophylaxis and vaccination is provided.
dc.description.urihttps://www.tandfonline.com/doi/abs/10.1080/10158782.2013.11441513
dc.description.versionPublisher's version
dc.format.extent12 pages
dc.identifier.citationBoyles, T. H. et al. 2013. Guidelines for the management of acute meningitis in children and adults in South Africa. Southern African Journal of Epidemiology and Infection, 28(1):5-15, doi:10.1080/10158782.2013.11441513.
dc.identifier.issn2220-1084 (onine)
dc.identifier.urihttp://hdl.handle.net/10019.1/93466
dc.language.isoen
dc.publisherTaylor & Francis
dc.rights.holderAuthors retain copyright
dc.subject.otherMeningitisen_ZA
dc.titleGuidelines for the management of acute meningitis in children and adults in South Africaen_ZA
dc.typeArticle
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