The impact of HIV infection on the presentation of lung cancer in South Africa
| dc.contributor.author | Koegelenberg, C. F. N. | en_ZA |
| dc.contributor.author | Van Der Made, T. | en_ZA |
| dc.contributor.author | Taljaard, J. J. | en_ZA |
| dc.contributor.author | Irusen, E. M. | en_ZA |
| dc.date.accessioned | 2017-10-16T08:32:31Z | |
| dc.date.available | 2017-10-16T08:32:31Z | |
| dc.date.issued | 2016 | |
| dc.description | CITATION: Koegelenberg, C. F. N., et al. 2016. The impact of HIV infection on the presentation of lung cancer in South Africa. South African Medical Journal, 106(7):666-668, doi:10.7196/SAMJ.2016.v106i7.10737. | |
| dc.description | The original publication is available at http://www.samj.org.za | |
| dc.description.abstract | ENGLISH ABSTRACT: Background. Despite the very high background prevalence of HIV and smoking-related diseases in sub-Saharan Africa, very little is known about the presentation of lung cancer in HIV-infected individuals. Methods. We prospectively compared HIV-positive (n=44) and HIV-negative lung cancer patients (n=425) with regard to demographics, cell type, performance status and umour node metastasis staging at initial presentation. Results. HIV-positive patients were found to be younger than HIV-negative (mean 54.1 (standard deviation (SD) 8.4) years v. 60.5 (10) years, p<0.01), more likely to have squamous cell carcinoma (43.2% v. 30.1%, p=0.07) and significantly more likely to have a poor Eastern Cooperative Oncology Group (ECOG) performance status of ≥3 (47.7% v. 29.4%, p=0.02). In the case of non-small cell-lung cancer, they were also significantly less likely to have early stage lung cancer (0% v. 10.3%, p=0.02) compared with HIV-negative patients. Conclusions. HIV-positive lung cancer patients were younger, significantly more likely to have a poor performance status at presentation and significantly less likely to have early stage lung cancer when compared with HIV-negative patients. | en_ZA |
| dc.description.abstract | AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar | af_ZA |
| dc.description.uri | http://www.samj.org.za/index.php/samj/article/view/10737 | |
| dc.description.version | Publisher's version | |
| dc.format.extent | 3 pages | en_ZA |
| dc.identifier.citation | Koegelenberg, C. F. N., et al. 2016. The impact of HIV infection on the presentation of lung cancer in South Africa. South African Medical Journal, 106(7):666-668, doi:10.7196/SAMJ.2016.v106i7.10737 | |
| dc.identifier.issn | 2078-5135 (online) | |
| dc.identifier.issn | 0256-9574 (print) | |
| dc.identifier.other | doi:10.7196/SAMJ.2016.v106i7.10737 | |
| dc.identifier.uri | http://hdl.handle.net/10019.1/102333 | |
| dc.language.iso | en_ZA | en_ZA |
| dc.publisher | Health & Medical Publishing Group | |
| dc.rights.holder | South African Medical Journal | |
| dc.subject | HIV-positive persons | en_ZA |
| dc.subject | Lung cancer | en_ZA |
| dc.subject | Bronchoscopy | en_ZA |
| dc.title | The impact of HIV infection on the presentation of lung cancer in South Africa | en_ZA |
| dc.type | Article | en_ZA |