Investigation and management of primary immunodeficiency in South African children

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dc.contributor.authorEley, B.en_ZA
dc.contributor.authorEsser, M.en_ZA
dc.date.accessioned2016-06-21T08:53:48Z
dc.date.available2016-06-21T08:53:48Z
dc.date.issued2014
dc.descriptionCITATION: Eley, B. & Esser, M. 2014. Investigation and management of primary immunodeficiency in South African children. South African Medical Journal, 104(11): 793-796, doi: 10.7196/SAMJ.8946.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractENGLISH ABSTRACT: The primary immunodeficiency diseases (PIDs) are inherited, non-communicable diseases that cause immunological dysfunction. PIDs are seldom reported in South Africa (SA). Based on a mid-2013 population estimate of 52.98 million and assuming that the prevalence of PIDs is similar to that in well-resourced settings, the total number of individuals with PIDs in our country should range between 2 850 and 45 723. However, fewer than 500 cases of PID have been reported in SA. Between five and 15 new, fully characterised PIDs are reported annually. Our understanding of the physiology of the immune system has been substantially enhanced by these discoveries, and consequently the international classification of PIDs has been updated.en_ZA
dc.description.urihttp://www.samj.org.za/index.php/samj/article/view/8946
dc.description.versionPublisher's version
dc.format.extent4 pagesen_ZA
dc.identifier.citationEley, B. & Esser, M. 2014. Investigation and management of primary immunodeficiency in South African children. South African Medical Journal, 104(11): 793-796, doi: 10.7196/SAMJ.8946
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.otherdoi: 10.7196/SAMJ.8946
dc.identifier.urihttp://hdl.handle.net/10019.1/99045
dc.language.isoen_ZAen_ZA
dc.publisherHealth and Medical Publishing Groupen_ZA
dc.rights.holderHealth & Medical Publishing Groupen_ZA
dc.subjectPrimary immunodeficiency -- Childrenen_ZA
dc.subjectImmune deficiency -- Investigationen_ZA
dc.subjectImmune deficiency -- Managementen_ZA
dc.titleInvestigation and management of primary immunodeficiency in South African childrenen_ZA
dc.typeArticleen_ZA
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