An evidence-based approach to recurrent pregnancy loss
| dc.contributor.author | Van Niekerk, Elzaan C. | en_ZA |
| dc.contributor.author | Siebert, Igno | en_ZA |
| dc.contributor.author | Kruger, Theunis Frans | en_ZA |
| dc.date.accessioned | 2017-05-02T06:33:31Z | |
| dc.date.available | 2017-05-02T06:33:31Z | |
| dc.date.issued | 2013-07-26 | |
| dc.description | CITATION: Van Niekerk, E. C., Siebert, I. & Kruger, T. F. 2013. An evidence-based approach to recurrent pregnancy loss. South African Journal of Obstetrics and Gynaecology, 19(3):61-65, doi:10.7196/SAJOG.670. | |
| dc.description | The original publication is available at http://www.sajog.org.za | |
| dc.description.abstract | Recurrent pregnancy loss (RPL) can be defined as more than two to three consecutive miscarriages before 24 weeks’ gestation. A literature review was done to provide an evidence-based approach to RPL, identifying the risk factors and causes and also looking at the various special investigations that form part of the work-up and trying to assess which have been proven to be effective or of negative impact, and which of the management options lead to a better outcome. We concluded that the following special investigations should be part of the work-up for all patients with RPL: (i) genetic counselling and karyotyping of the abortus; (ii) anticardiolipin antibodies and lupus anticoagulant testing must be done on two occasions, 6 - 8 weeks apart; (iii) all patients qualify for a pelvic ultrasound scan and hysteroscopy; (iv) syphilis testing must be done routinely; and (v) testing of thyroid function and glucose monitoring/glycosylated haemoglobin (HbA1c) measurement must be done in all patients with a history of thyroid disease or diabetes mellitus, or clinical manifestations thereof. In approximately 50% of couples the cause of RPL remains unexplained, even after evaluation. | en_ZA |
| dc.description.uri | http://www.sajog.org.za/index.php/SAJOG/article/view/670 | |
| dc.description.version | Publisher's version | |
| dc.format.extent | 5 pages | |
| dc.identifier.citation | Van Niekerk, E. C., Siebert, I. & Kruger, T. F. 2013. An evidence-based approach to recurrent pregnancy loss. South African Journal of Obstetrics and Gynaecology, 19(3):61-65, doi:10.7196/SAJOG.670. | |
| dc.identifier.issn | 2305-8862 (online) | |
| dc.identifier.issn | 0038-2329 (print) | |
| dc.identifier.other | doi:10.7196/SAJOG.670 | |
| dc.identifier.uri | http://hdl.handle.net/10019.1/101517 | |
| dc.language.iso | en_ZA | en_ZA |
| dc.publisher | Health & Medical Publishing Group | |
| dc.rights.holder | Authors retain copyright | |
| dc.subject | Miscarriage | en_ZA |
| dc.subject | Pregnancy -- Complications | en_ZA |
| dc.title | An evidence-based approach to recurrent pregnancy loss | en_ZA |
| dc.type | Article | en_ZA |