7-year follow up of intra-operative radiotherapy for early breast cancer in a developing country
| dc.contributor.author | Baatjes K.J. | |
| dc.contributor.author | Apffelstaedt J.P. | |
| dc.date.accessioned | 2012-07-05T08:00:52Z | |
| dc.date.available | 2012-07-05T08:00:52Z | |
| dc.date.issued | 2012 | |
| dc.description.abstract | Scarce radiation resources and an often poor, rural population make single fraction, definitive intra-operative radiation (IORT) ideal for developing countries. From 2002 to 2005 IORT in breast conservation was administered utilizing existing infrastructure in an extremely resource-restricted environment. After tumor excision an applicator was introduced into the tumor bed. An existing Ir 192 after loader delivered a single fraction (21 Gy).Of thirty nine patients treated with 84 months follow-up, one patient suffered local, four regional and three systemic relapse. One patient died of disease, 2 of unrelated causes for a local control rate of 95% and a disease-specific survival of 95%. Cosmetic outcome was perceived excellent. IORT using existing after loaders and a low cost applicator greatly reduced health care resources. This extends breast conservation to indigent patients who cannot adhere to lengthy EBRT protocols. © 2012 Elsevier Ltd. | |
| dc.identifier.citation | Breast | |
| dc.identifier.citation | 21 | |
| dc.identifier.citation | 3 | |
| dc.identifier.citation | 326 | |
| dc.identifier.citation | 329 | |
| dc.identifier.issn | 9609776 | |
| dc.identifier.other | doi:10.1016/j.breast.2012.01.021 | |
| dc.identifier.uri | http://hdl.handle.net/10019.1/21573 | |
| dc.subject | Breast conservation therapy | |
| dc.subject | Intra-operative radiotherapy | |
| dc.title | 7-year follow up of intra-operative radiotherapy for early breast cancer in a developing country | |
| dc.type | Article |