Tuberculosis transmission in a hospitalised neonate : need for optimised tuberculosis screening of pregnant and postpartum women

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dc.contributor.authorZenhausern, J.en_ZA
dc.contributor.authorBekker, A.en_ZA
dc.contributor.authorWates, M. A.en_ZA
dc.contributor.authorSchaaf, H. S.en_ZA
dc.contributor.authorDramowski, A.en_ZA
dc.date.accessioned2021-09-16T10:29:34Z
dc.date.available2021-09-16T10:29:34Z
dc.date.issued2019
dc.descriptionCITATION: Zenhausern, J., et al. 2019. Tuberculosis transmission in a hospitalised neonate : need for optimised tuberculosis screening of pregnant and postpartum women. South African Medical Journal, 109(5):310-313, doi:10.7196/SAMJ.2019.v109i5.13789.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractENGLISH ABSTRACT: A recent fatal case of confirmed nosocomial tuberculosis (TB) transmission to a neonate in a kangaroo mother care (KMC) unit highlighted the infection risk to hospitalised neonates in South Africa, a high-burden TB setting. The index case was a 9-week-old infant who presented to another hospital’s intensive care unit with severe respiratory distress shortly after discharge from the KMC unit. Contact tracing identified that the infant had been exposed to a postpartum woman with undiagnosed pulmonary TB while in the KMC unit. Molecular testing confirmed nosocomial transmission between the index case and the presumed source case in the KMC unit. We describe the subsequent process of tracing other TB-exposed infants and mothers, the difficulty in confirming TB infection/disease in pregnancy, and the provision of isoniazid preventive therapy in this cohort. We discuss the practical implementation of TB screening approaches in maternity and neonatal wards in high-burden TB settings.en_ZA
dc.description.urihttp://www.samj.org.za/index.php/samj/article/view/12603
dc.description.versionPublisher's version
dc.format.extent4 pagesen_ZA
dc.identifier.citationZenhausern, J., et al. 2019. Tuberculosis transmission in a hospitalised neonate : need for optimised tuberculosis screening of pregnant and postpartum women. South African Medical Journal, 109(5):310-313, doi:10.7196/SAMJ.2019.v109i5.13789
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.otherdoi:10.7196/SAMJ.2019.v109i5.13789
dc.identifier.urihttp://hdl.handle.net/10019.1/123036
dc.language.isoen_ZAen_ZA
dc.publisherHealth & Medical Publishing Groupen_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectMycobacterium tuberculosisen_ZA
dc.subjectTuberculosis -- Transmissionen_ZA
dc.subjectNewborn infant screenings -- Tuberculosisen_ZA
dc.subjectPostnatal careen_ZA
dc.subjectPost partum period -- Medical screening -- Tuberculosisen_ZA
dc.subjectNosocomial infections in childrenen_ZA
dc.titleTuberculosis transmission in a hospitalised neonate : need for optimised tuberculosis screening of pregnant and postpartum womenen_ZA
dc.typeArticleen_ZA
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