Brachial amyotrophic diplegia (segmental proximal spinal muscular atrophy) associated with HIV infection

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dc.contributor.authorHenning F.
dc.contributor.authorHewlett R.H.
dc.date.accessioned2011-05-15T16:17:04Z
dc.date.available2011-05-15T16:17:04Z
dc.date.issued2008
dc.description.abstractSeveral forms of motor neuron disease occurring in association with HIV infection have been described. Segmental proximal spinal muscular atrophy or brachial amyotrophic diplegia, a rare segmental variant of motor neuron disease with isolated bilateral upper extremity weakness, has previously been described in a single case report. We describe a patient who is HIV-seropositive presenting with this phenotype and illustrate novel findings on MRI of the cervical cord, consisting of focal atrophy and T2 hyperintense signal change involving the anterior grey matter. Additionally, a number of differences compared with patients without HIV presenting with this motor neuron disease variant are highlighted.
dc.description.versionArticle
dc.identifier.citationJournal of Neurology, Neurosurgery and Psychiatry
dc.identifier.citation79
dc.identifier.citation12
dc.identifier.issn00223050
dc.identifier.other10.1136/jnnp.2008.147272
dc.identifier.urihttp://hdl.handle.net/10019.1/14057
dc.subjectantiretrovirus agent
dc.subjectadult
dc.subjectarticle
dc.subjectbrachial myotrophic diplegia
dc.subjectcase report
dc.subjectcervical spinal cord
dc.subjectclinical feature
dc.subjectgray matter
dc.subjecthighly active antiretroviral therapy
dc.subjecthuman
dc.subjectHuman immunodeficiency virus 1
dc.subjectHuman immunodeficiency virus 1 infection
dc.subjectmale
dc.subjectneuroimaging
dc.subjectneurologic examination
dc.subjectnuclear magnetic resonance imaging
dc.subjectphenotype
dc.subjectpriority journal
dc.subjectspinal muscular atrophy
dc.subjectAcquired Immunodeficiency Syndrome
dc.subjectAdult
dc.subjectAntiretroviral Therapy, Highly Active
dc.subjectBrain
dc.subjectHIV Infections
dc.subjectHumans
dc.subjectMagnetic Resonance Imaging
dc.subjectMale
dc.subjectMotor Neuron Disease
dc.subjectMuscular Atrophy, Spinal
dc.subjectPhenotype
dc.subjectVitamin B 12 Deficiency
dc.titleBrachial amyotrophic diplegia (segmental proximal spinal muscular atrophy) associated with HIV infection
dc.typeArticle
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