Ascaris lumbricoides and allergic asthma. A new perspective

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dc.contributor.authorJoubert, J. R.en_ZA
dc.contributor.authorDe Klerk, H. C.en_ZA
dc.contributor.authorMalan, C.en_ZA
dc.date.accessioned2011-03-18T14:57:49Z
dc.date.available2011-03-18T14:57:49Z
dc.date.issued1979-10
dc.descriptionCITATION: Joubert, J.R., De Klerk, H.C. & Malan, C. 1979. Ascaris lumbricoides and allergic asthma. A new perspective. S Afr Med J, 56(10):599-602.en_ZA
dc.descriptionThe original publication is available at http://www.samj.org.zaen_ZA
dc.description.abstractENGLISH ABSTRACT: Infestation of humans with the parasite Ascaris lumbricoides may induce high total serium IgE levels, but the influence of this immunogenic respone on allergic asthma has not been defined. In this study, the specific antiparasitic IgE-mediated response as determined by skin-prick testing was related to the incidence of allergic asthma in Ascaris-infested patients. A limited number - 17% of the non-allergic controls and 51% of the allergic asthmatics - had a clinically detectable immunogenic response to the parasite. The predicted incidence of asthma was significantly higher than the observed incidence in the subjects in whom the Ascaris skin test was positive. This was not found in subjects in whom the Ascaris skin test was negative. Inhalation of Ascaris antigen induced asthmatic reactions in 7 of 8 patients who were Ascaris-positive on skin testing, but not in the negative controls. The groups of patients who repond immunogenically to parasite infestation need to be defined, as they may be predisposed to allergic diseases such as asthma.en_ZA
dc.description.versionPublisher’s version
dc.format.extent4 pagesen_ZA
dc.identifier.citationJoubert, J.R., De Klerk, H.C. & Malan, C. 1979. Ascaris lumbricoides and allergic asthma. A new perspective. S Afr Med J, 56(10):599-602.en_ZA
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/7670
dc.language.isoen_ZAen_ZA
dc.publisherHealth & Medical Publishing Groupen_ZA
dc.rights.holderSouth African Medical Journalen_ZA
dc.subjectAscaris lumbricoidesen_ZA
dc.subjectAsthmatics -- Allergiesen_ZA
dc.subjectAsthma -- Treatmenten_ZA
dc.titleAscaris lumbricoides and allergic asthma. A new perspectiveen_ZA
dc.typeArticleen_ZA
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