Comparing axillary and mediastinal lymphadenopathy on CT in children with suspected pulmonary tuberculosis
dc.contributor.author | Theron S. | |
dc.contributor.author | Andronikou S. | |
dc.date.accessioned | 2011-05-15T16:17:42Z | |
dc.date.available | 2011-05-15T16:17:42Z | |
dc.date.issued | 2005 | |
dc.description.abstract | Background: Radiographic demonstration of mediastinal lymphadenopathy is important for the diagnosis of pulmonary tuberculosis (PTB). Plain radiographs are unreliable for this and CT, which is relatively more expensive and carries a high radiation burden, remains the gold standard. No studies correlating the presence of axillary with mediastinal lymphadenopathy have been reported. Such a correlation would allow for clinical or ultrasound diagnosis of PTB via the axilla. Objective: To correlate the presence of axillary lymphadenopathy with mediastinal lymphadenopathy in children with suspected PTB. Materials and methods: CT scans were performed and reviewed in 100 children (prospectively recruited) with suspected PTB. The axilla and mediastinum were reviewed separately by covering the non-relevant sections on the CT scans prior to reading. Only nodes greater than 1 cm were regarded as pathological. Results: Mediastinal lymphadenopathy was present in 46% of children; 70% had lymphadenopathy in either axilla. Bilateral axillary lymphadenopathy was identified in 47%. Axillary lymphadenopathy showed a sensitivity of 74% and a specificity of 33% for the presence of mediastinal adenopathy. Bilateral axillary adenopathy had a sensitivity of 50% and a specificity of 56%. Conclusions: Axillary lymphadenopathy has a moderate sensitivit y and low specificity for the presence of mediastinal and hilar lymphadenopathy in children with suspected PTB. Further research should be aimed at correlating ultrasound-detected axillary lymphadenopathy with FNA results in children. © Springer-Verlag 2005. | |
dc.description.version | Article | |
dc.identifier.citation | Pediatric Radiology | |
dc.identifier.citation | 35 | |
dc.identifier.citation | 9 | |
dc.identifier.issn | 03010449 | |
dc.identifier.other | 10.1007/s00247-005-1490-y | |
dc.identifier.uri | http://hdl.handle.net/10019.1/14336 | |
dc.subject | article | |
dc.subject | axillary lymph node | |
dc.subject | child care | |
dc.subject | clinical trial | |
dc.subject | computer assisted tomography | |
dc.subject | controlled clinical trial | |
dc.subject | controlled study | |
dc.subject | correlation analysis | |
dc.subject | female | |
dc.subject | human | |
dc.subject | infant | |
dc.subject | lung tuberculosis | |
dc.subject | lymphadenopathy | |
dc.subject | major clinical study | |
dc.subject | male | |
dc.subject | mediastinum lymph node | |
dc.subject | priority journal | |
dc.subject | prospective study | |
dc.subject | sensitivity and specificity | |
dc.subject | Axilla | |
dc.subject | Child | |
dc.subject | Child, Preschool | |
dc.subject | Female | |
dc.subject | Humans | |
dc.subject | Infant | |
dc.subject | Lymphatic Diseases | |
dc.subject | Male | |
dc.subject | Mediastinum | |
dc.subject | Predictive Value of Tests | |
dc.subject | Prospective Studies | |
dc.subject | Sensitivity and Specificity | |
dc.subject | Tomography, X-Ray Computed | |
dc.subject | Tuberculosis, Lymph Node | |
dc.subject | Tuberculosis, Pulmonary | |
dc.title | Comparing axillary and mediastinal lymphadenopathy on CT in children with suspected pulmonary tuberculosis | |
dc.type | Article |