Diagnostic yield of fine needle aspiration biopsy in HIV-infected adults with suspected mycobacterial lymphadenitis
dc.contributor.author | Razack, R. | en_ZA |
dc.contributor.author | Louw, M. | en_ZA |
dc.contributor.author | Wright, C. A. | en_ZA |
dc.date.accessioned | 2015-11-25T12:14:46Z | |
dc.date.available | 2015-11-25T12:14:46Z | |
dc.date.issued | 2014-01 | |
dc.description | Please cite as follows: Razack, R., Louw, M. & Wright, C. A. 2014. Diagnostic yield of fine needle aspiration biopsy in HIV-infected adults with suspected mycobacterial lymphadenitis. South African Medical Journal 104(1):27-28. DOI:10.7196/SAMJ.7492. | en_ZA |
dc.description | The original publication is available at http://www.samj.org.za | en_ZA |
dc.description.abstract | Background: Fine needle aspiration biopsy (FNAB) has been shown to be the diagnostic procedure of choice for superficial lymphadenitis in tuberculosis endemic regions. Methods: We conducted a retrospective laboratory-based study to determine the bacteriological yield of clinically suspected mycobacterial tuberculous lymphadenitis following FNAB in adults, and specifically HIV-positive patients, to determine the need for the introduction of automated nucleic acid amplification tests (NAATs) such as the Xpert MTB/RIF assay as the initial diagnostic modality. Results: A diagnostic yield of 80% was achieved, significantly higher in HIV-positive v. HIV-negative patients (84% v. 52%, respectively; p<0.001). Conclusion: The results justify using automated NAATs such as the Xpert MTB/RIF assay as the initial diagnostic modality to expedite management in HIV-infected patients. | en_ZA |
dc.description.uri | http://www.samj.org.za/index.php/samj/article/view/7492 | |
dc.description.version | Publisher's version | en_ZA |
dc.format.extent | 2 pages | en_ZA |
dc.identifier.citation | Razack, R., Louw, M. & Wright, C. A. 2014. Diagnostic yield of fine needle aspiration biopsy in HIV-infected adults with suspected mycobacterial lymphadenitis. South African Medical Journal 104(1):27-28. DOI:10.7196/SAMJ.7492. | en_ZA |
dc.identifier.issn | 2078-5135 (online) | |
dc.identifier.issn | 0256-9574 (print) | |
dc.identifier.other | doi:10.7196/SAMJ.7492 | |
dc.identifier.uri | http://hdl.handle.net/10019.1/97648 | |
dc.language.iso | en_ZA | en_ZA |
dc.publisher | Health & Medical Publishing Group | en_ZA |
dc.rights.holder | South African Medical Journal | en_ZA |
dc.subject | Needle biopsy | en_ZA |
dc.subject | Tuberculosis -- Diagnostic imaging | en_ZA |
dc.subject | HIV (Viruses) | en_ZA |
dc.subject | Lymphadenopathy | en_ZA |
dc.subject | HIV-positive persons | en_ZA |
dc.title | Diagnostic yield of fine needle aspiration biopsy in HIV-infected adults with suspected mycobacterial lymphadenitis | en_ZA |
dc.type | Article | en_ZA |