Mortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017 : an analysis for the Global Burden of Disease Study 2017

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dc.contributor.authorTroeger, Christopher E.en_ZA
dc.contributor.authorBlacker, Brigette F.en_ZA
dc.contributor.authorKhalil, Ibrahim A.en_ZA
dc.contributor.authorZimsen, Stephanie R. M.en_ZA
dc.contributor.authorAlbertson, Samuel B.en_ZA
dc.contributor.authorAbate, Deguen_ZA
dc.contributor.authorAbdela, Jemalen_ZA
dc.contributor.authorAdhikari, Tara Ballaven_ZA
dc.contributor.authorAghayan, Sargis Aghasien_ZA
dc.contributor.authorAgrawal, Sutapaen_ZA
dc.contributor.authorAhmadi, Alirezaen_ZA
dc.contributor.authorAichour, Amani Nidhalen_ZA
dc.contributor.authorAichour, Ibtihelen_ZA
dc.contributor.authorAichour, Miloud Taki Eddineen_ZA
dc.contributor.authorAl-Eyadhy, Aymanen_ZA
dc.contributor.authorAl-Raddadi, Rajaa M.en_ZA
dc.contributor.authorAlahdab, Faresen_ZA
dc.contributor.authorAlene, Kefyalew Addisen_ZA
dc.contributor.authorAljunid, Syed Mohameden_ZA
dc.contributor.authorAlvis-Guzman, Nelsonen_ZA
dc.contributor.authorAnber, Nahla Hameden_ZA
dc.contributor.authorAnjomshoa, Minaen_ZA
dc.contributor.authorAntonio, Carl Abelardo T.en_ZA
dc.contributor.authorAremu, Olatundeen_ZA
dc.contributor.authorAtalay, Hagos Tasewen_ZA
dc.contributor.authorAtique, Sulemanen_ZA
dc.contributor.authorAttia, Engi F.en_ZA
dc.contributor.authorAvokpaho, Euripide F. G. A.en_ZA
dc.contributor.authorAwasthi, Ashishen_ZA
dc.contributor.authorBabazadeh, Arefehen_ZA
dc.contributor.authorBadali, Hamiden_ZA
dc.contributor.authorBadawi, Alaaen_ZA
dc.contributor.authorBanoub, Joseph Adel Mattaren_ZA
dc.contributor.authorBarac, Aleksandraen_ZA
dc.contributor.authorBassat, Quiqueen_ZA
dc.contributor.authorBedi, Neerajen_ZA
dc.contributor.authorBelachew, Abate Bekeleen_ZA
dc.contributor.authorBennett, Derrick A.en_ZA
dc.contributor.authorBhattacharyya, Krittikaen_ZA
dc.contributor.authorBhutta, Zulfiqar A.en_ZA
dc.contributor.authorBijani, Alien_ZA
dc.contributor.authorCarvalho, Felixen_ZA
dc.contributor.authorCastaneda-Orjuela, Carlos A.en_ZA
dc.contributor.authorChristopher, Devasahayam J.en_ZA
dc.contributor.authorDandona, Laliten_ZA
dc.contributor.authorDandona, Rakhien_ZA
dc.contributor.authorDang, Anh Kimen_ZA
dc.contributor.authorDaryani, Ahmaden_ZA
dc.contributor.authorDegefa, Meaza Girmaen_ZA
dc.contributor.authorDemeke, Feleke Mekonnenen_ZA
dc.contributor.authorDhimal, Meghnathen_ZA
dc.contributor.authorDjalalinia, Shirinen_ZA
dc.contributor.authorDoku, David Teyeen_ZA
dc.contributor.authorDubey, Manishaen_ZA
dc.contributor.authorDubljanin, Eleonoraen_ZA
dc.contributor.authorDuken, Eyasu Ejetaen_ZA
dc.contributor.authorEdessa, Dumessaen_ZA
dc.contributor.authorZaki, Maysaa El Sayeden_ZA
dc.contributor.authorFakhim, Hameden_ZA
dc.contributor.authorFernandes, Eduardaen_ZA
dc.contributor.authorFischer, Florianen_ZA
dc.contributor.authorFlor, Luisa Sorioen_ZA
dc.contributor.authorForeman, Kyle J.en_ZA
dc.contributor.authorGebremichael, Teklu Gebrehiwoen_ZA
dc.contributor.authorGeremew, Demekeen_ZA
dc.contributor.authorGhadiri, Keyghobaden_ZA
dc.contributor.authorGoulart, Alessandra C.en_ZA
dc.contributor.authorGuo, Jingwenen_ZA
dc.contributor.authorHa, Giang Haien_ZA
dc.contributor.authorHailu, Gessessew Bugssaen_ZA
dc.contributor.authorHaj-Mirzaian, Arvinen_ZA
dc.contributor.authorHaj-Mirzaian, Aryaen_ZA
dc.contributor.authorHamidi, Sameren_ZA
dc.contributor.authorHassen, Hamid Yimamen_ZA
dc.contributor.authorHoang, Chi Linhen_ZA
dc.contributor.authorHorita, Nobuyukien_ZA
dc.contributor.authorHostiuc, Mihaelaen_ZA
dc.contributor.authorIrvani, Seyed Sina Naghibien_ZA
dc.contributor.authorJha, Ravi Prakashen_ZA
dc.contributor.authorJonas, Jost B.en_ZA
dc.contributor.authorKahsay, Amahaen_ZA
dc.contributor.authorKarch, Andreen_ZA
dc.contributor.authorKasaeian, Amiren_ZA
dc.contributor.authorKassa, Tesfaye Dessaleen_ZA
dc.contributor.authorKefale, Adane Teshomeen_ZA
dc.contributor.authorKhader, Yousef Salehen_ZA
dc.contributor.authorKhan, Ejaz Ahmaden_ZA
dc.contributor.authorKhan, Gulfarazen_ZA
dc.contributor.authorKhan, Md Nuruzzamanen_ZA
dc.contributor.authorKhang, Young-Hoen_ZA
dc.contributor.authorKhoja, Abdullah T.en_ZA
dc.contributor.authorKhubchandani, Jagdishen_ZA
dc.contributor.authorKimokoti, Ruth W.en_ZA
dc.contributor.authorKisa, Adnanen_ZA
dc.contributor.authorKnibbs, Luke D.en_ZA
dc.contributor.authorKochhar, Sonalien_ZA
dc.contributor.authorKosen, Soewartaen_ZA
dc.contributor.authorKoul, Parvaiz A.en_ZA
dc.contributor.authorKoyanagi, Aien_ZA
dc.contributor.authorDefo, Barthelemy Kuateen_ZA
dc.contributor.authorKumar, G. Anilen_ZA
dc.contributor.authorLal, Dharmesh Kumaren_ZA
dc.contributor.authorLamichhane, Prabhaten_ZA
dc.contributor.authorLeshargie, Cheru Tesemaen_ZA
dc.contributor.authorLevi, Miriamen_ZA
dc.contributor.authorLi, Shanshanen_ZA
dc.contributor.authorMacarayan, Erlyn Rachelle Kingen_ZA
dc.contributor.authorMajdan, Mareken_ZA
dc.contributor.authorMehta, Varshilen_ZA
dc.contributor.authorMelese, Addisuen_ZA
dc.contributor.authorMemish, Ziad A.en_ZA
dc.contributor.authorMengistu, Desalegn Tadeseen_ZA
dc.contributor.authorMeretoja, Tuomo J.en_ZA
dc.contributor.authorMestrovic, Tomislaven_ZA
dc.contributor.authorMiazgowski, Bartoszen_ZA
dc.contributor.authorMilne, George J.en_ZA
dc.contributor.authorMilosevic, Brankoen_ZA
dc.contributor.authorMirrakhimov, Erkin M.en_ZA
dc.contributor.authorMoazen, Babaken_ZA
dc.contributor.authorMohammad, Karzan Abdulmuhsinen_ZA
dc.contributor.authorMohammed, Shafiuen_ZA
dc.contributor.authorMonasta, Lorenzoen_ZA
dc.contributor.authorMorawska, Lidiaen_ZA
dc.contributor.authorMousavi, Seyyed Meysamen_ZA
dc.contributor.authorMuhammed, Oumer Sada S.en_ZA
dc.contributor.authorMurthy, Srinivasen_ZA
dc.contributor.authorMustafa, Ghulamen_ZA
dc.contributor.authorNaheed, Aliyaen_ZA
dc.contributor.authorNguyen, Huong Lan Thien_ZA
dc.contributor.authorNguyen, Nam Baen_ZA
dc.contributor.authorNguyen, Son Hoangen_ZA
dc.contributor.authorNguyen, Trang Huyenen_ZA
dc.contributor.authorNisar, Muhammad Imranen_ZA
dc.contributor.authorNixon, Molly R.en_ZA
dc.contributor.authorOgbo, Felix Akpojeneen_ZA
dc.contributor.authorOlagunju, Andrew T.en_ZA
dc.contributor.authorOlagunju, Tinuke O.en_ZA
dc.contributor.authorOren, Eyalen_ZA
dc.contributor.authorOrtiz, Justin R.en_ZA
dc.contributor.authorMahesh, P. A.en_ZA
dc.contributor.authorPakhale, Smitaen_ZA
dc.contributor.authorPatel, Shantien_ZA
dc.contributor.authorPaudel, Deepaken_ZA
dc.contributor.authorPigott, David M.en_ZA
dc.contributor.authorPostma, Maarten J.en_ZA
dc.contributor.authorQorbani, Mostafaen_ZA
dc.contributor.authorRafay, Anwaren_ZA
dc.contributor.authorRafiei, Alirezaen_ZA
dc.contributor.authorRahimi-Movaghar, Vafaen_ZA
dc.contributor.authorRai, Rajesh Kumaren_ZA
dc.contributor.authorRezai, Mohammad Sadeghen_ZA
dc.contributor.authorRoberts, Nicholas L. S.en_ZA
dc.contributor.authorRonfani, Lucaen_ZA
dc.contributor.authorRubino, Salvatoreen_ZA
dc.contributor.authorSafari, Saeeden_ZA
dc.contributor.authorSafiri, Saeiden_ZA
dc.contributor.authorSaleem, Zikriaen_ZA
dc.contributor.authorSambala, Evanson Zondanien_ZA
dc.contributor.authorSamy, Abdallah M.en_ZA
dc.contributor.authorMilicevic, Milena M. Santricen_ZA
dc.contributor.authorSartorius, Bennen_ZA
dc.contributor.authorSarvi, Shahabeddinen_ZA
dc.contributor.authorSavic, Milojeen_ZA
dc.contributor.authorSawhney, Monikaen_ZA
dc.contributor.authorSaxena, Soniaen_ZA
dc.contributor.authorSeyedmousavi, Seyedmojtabaen_ZA
dc.contributor.authorShaikh, Masood Alien_ZA
dc.contributor.authorSharif, Mehdien_ZA
dc.contributor.authorSheikh, Azizen_ZA
dc.contributor.authorShigematsu, Mikaen_ZA
dc.contributor.authorSmith, David L.en_ZA
dc.contributor.authorSomayaji, Ranjanien_ZA
dc.contributor.authorSoriano, Joan B.en_ZA
dc.contributor.authorSreeramareddy, Chandrashekhar T.en_ZA
dc.contributor.authorSufiyan, Muawiyyah Babaleen_ZA
dc.contributor.authorTemsah, Mohamad-Hanien_ZA
dc.contributor.authorTessema, Belayen_ZA
dc.contributor.authorTeweldemedhin, Mebrahtuen_ZA
dc.contributor.authorTortajada-Girbes, Miguelen_ZA
dc.contributor.authorTran, Bach Xuanen_ZA
dc.contributor.authorTran, Khanh Baoen_ZA
dc.contributor.authorTsadik, Afewerki Gebremeskelen_ZA
dc.contributor.authorUkwaja, Kingsley Nnannaen_ZA
dc.contributor.authorUllah, Irfanen_ZA
dc.contributor.authorVasankari, Tommi Juhanien_ZA
dc.contributor.authorVu, Giang Thuen_ZA
dc.contributor.authorWada, Fiseha Wadiloen_ZA
dc.contributor.authorWaheed, Yasiren_ZA
dc.contributor.authorWest, T. Eoinen_ZA
dc.contributor.authorWiysonge, Charles Sheyen_ZA
dc.contributor.authorYimer, Ebrahim M.en_ZA
dc.contributor.authorYonemoto, Naohiroen_ZA
dc.contributor.authorZaidi, Zoubidaen_ZA
dc.contributor.authorVos, Theoen_ZA
dc.contributor.authorLim, Stephen S.en_ZA
dc.contributor.authorMurray, Christopher J. L.en_ZA
dc.contributor.authorMokdad, Ali H.en_ZA
dc.contributor.authorHay, Simon I.en_ZA
dc.contributor.authorReiner, Robert C.en_ZA
dc.date.accessioned2021-10-12T11:51:29Z
dc.date.available2021-10-12T11:51:29Z
dc.date.issued2019
dc.descriptionCITATION: Troeger, C. E., et al. 2019. Mortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017 : an analysis for the Global Burden of Disease Study 2017. Lancet Respiratory Medicine, 7(1):69-89, doi:10.1016/S2213-2600(18)30496-X.
dc.descriptionThe original publication is available at https://www.thelancet.com
dc.description.abstractBackground: Although the burden of influenza is often discussed in the context of historical pandemics and the threat of future pandemics, every year a substantial burden of lower respiratory tract infections (LRTIs) and other respiratory conditions (like chronic obstructive pulmonary disease) are attributable to seasonal influenza. The Global Burden of Disease Study (GBD) 2017 is a systematic scientific effort to quantify the health loss associated with a comprehensive set of diseases and disabilities. In this Article, we focus on LRTIs that can be attributed to influenza. Methods We modelled the LRTI incidence, hospitalisations, and mortality attributable to influenza for every country and selected subnational locations by age and year from 1990 to 2017 as part of GBD 2017. We used a counterfactual approach that first estimated the LRTI incidence, hospitalisations, and mortality and then attributed a fraction of those outcomes to influenza. Findings Influenza LRTI was responsible for an estimated 145 000 (95% uncertainty interval [UI] 99 000–200 000) deaths among all ages in 2017. The influenza LRTI mortality rate was highest among adults older than 70 years (16·4 deaths per 100 000 [95% UI 11·6–21·9]), and the highest rate among all ages was in eastern Europe (5·2 per 100 000 population [95% UI 3·5–7·2]). We estimated that influenza LRTIs accounted for 9 459 000 (95% UI 3 709 000–22 935 000) hospitalisations due to LRTIs and 81 536 000 hospital days (24 330 000–259 851 000). We estimated that 11·5% (95% UI 10·0–12·9) of LRTI episodes were attributable to influenza, corresponding to 54 481 000 (38 465 000–73 864 000) episodes and 8 172 000 severe episodes (5 000 000–13 296 000). Interpretation This comprehensive assessment of the burden of influenza LRTIs shows the substantial annual effect of influenza on global health. Although preparedness planning will be important for potential pandemics, health loss due to seasonal influenza LRTIs should not be overlooked, and vaccine use should be considered. Efforts to improve influenza prevention measures are needed.en_ZA
dc.description.urihttps://www.thelancet.com/journals/lanres/article/PIIS2213-2600(18)30496-X/fulltext#%20
dc.description.versionPublisher's version
dc.format.extent21 pagesen_ZA
dc.identifier.citationTroeger, C. E., et al. 2019. Mortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017 : an analysis for the Global Burden of Disease Study 2017. Lancet Respiratory Medicine, 7(1):69-89, doi:10.1016/S2213-2600(18)30496-X
dc.identifier.issn2213-2600 (online)
dc.identifier.otherdoi:10.1016/S2213-2600(18)30496-X
dc.identifier.urihttp://hdl.handle.net/10019.1/123210
dc.language.isoen_ZAen_ZA
dc.publisherElsevieren_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectMorbidityen_ZA
dc.subjectRespiratory tract infectionsen_ZA
dc.subjectInfluenza -- Researchen_ZA
dc.subjectEpidemicsen_ZA
dc.subjectMortalityen_ZA
dc.titleMortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017 : an analysis for the Global Burden of Disease Study 2017en_ZA
dc.typeArticleen_ZA
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