Prostaglandin effects in the neuroendocrine mammalian brain

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dc.contributor.authorMacfarlane C. M.
dc.contributor.authorTaljaard J. J. F.
dc.date.accessioned2011-03-18T14:59:42Z
dc.date.available2011-03-18T14:59:42Z
dc.date.issued1985
dc.descriptionPublishers' version
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractVarious prostaglandins (PGs) have been found in several areas of the brain. PGs of the E series have been found in the pituitary and pineal glands and the median eminence, and they have been shown to influence hypothalamic endocrine-release characteristics and release of melatonin from the pineal gland. It has been suggested that they may act, along with membrane phospholipids, as a link between neuronal depolarization, calcium uptake and neurotransmitter release. They may also influence postsynaptic effects of neurotransmitters. These latter effects may be due to interaction with membrane phospholipid- and cyclic nucleotide-induced changes of specific protein kinases. The PGs may act as intracellular mediators of neuro-endocrine control.en_ZA
dc.description.versionPublishers' version
dc.format.extentpp. 503-506 : ill.
dc.identifier.citationMacfarlane, C.M., Taljaard, J.J.M. 1985. Prostaglandin effects in the neuroendocrine mammalian brain. South African Medical Journal, vol. 67, March 30. pp. 503-506
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/8002
dc.language.isoen_ZA
dc.publisherHMPG
dc.rights.holderThe author
dc.subjectCalcium absorptionen_ZA
dc.subjectProstaglandinen_ZA
dc.subjectProstaglandin d2en_ZA
dc.subjectProstaglandin e2en_ZA
dc.subjectProstaglandin f2 alphaen_ZA
dc.subjectProstaglandin g2en_ZA
dc.subjectProstaglandin h2en_ZA
dc.subjectProtein kinaseen_ZA
dc.subjectCentral nervous systemen_ZA
dc.subjectEndocrine systemen_ZA
dc.subjectHypothalamusen_ZA
dc.subjectNeuroendocrinologyen_ZA
dc.subjectEndocrine Glandsen_ZA
dc.subjectMembrane Lipidsen_ZA
dc.subjectNeuronsen_ZA
dc.subjectNeurosecretory systemsen_ZA
dc.subjectNeurotransmittersen_ZA
dc.subjectNorepinephrineen_ZA
dc.subjectPhospholipidsen_ZA
dc.subjectPineal Glanden_ZA
dc.subjectPituitary Hormonesen_ZA
dc.subjectRats as laboratory animalsen_ZA
dc.subjectSynaptic transmissionen_ZA
dc.subjectTissue distributionen_ZA
dc.subjectEndocrine gland metabolismen_ZA
dc.subjectNeuro-endocrine controlen_ZA
dc.subjectHypothalamic output and secretionen_ZA
dc.subjectInterneuron interactionen_ZA
dc.titleProstaglandin effects in the neuroendocrine mammalian brainen_ZA
dc.typeArticleen_ZA
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