Smoking, oncogenes and human lung cancer. A review of recent laboratory evidence linking smoking and lung cancer

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dc.contributor.authorAlbrecht, C. F.en_ZA
dc.contributor.authorTheron, E. L.en_ZA
dc.date.accessioned2011-03-18T14:57:25Z
dc.date.available2011-03-18T14:57:25Z
dc.date.issued1988
dc.descriptionCITATION: Albrecht, C. F. & Theron, E. L. 1988. Smoking, oncogenes and human lung cancer. A review of recent laboratory evidence linking smoking and lung cancer. South African Medical Journal, 73:406-408.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractRecent molecular genetic experiments conducted in the USA and The Netherlands have isolated specific mutations in human lung cancer cells. These data implicate the activation of the K-ras oncogene in the pathogenesis of adenocarcinoma of the lungs of heavy smokers and the deletion of DNA from the short arm of chromosome 3 in small-cell and non-small-cell carcinoma of the lung. The implications of these results are discussed and explained in the light of current DNA-manipulative technology which is now available in RSA.
dc.description.versionPublisher’s version
dc.format.extent3 pages
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/7404
dc.language.isoen
dc.publisherHealth & Medical Publishing Group
dc.rights.holderSouth African Medical Journal
dc.subjectLungs -- Canceren_ZA
dc.subjectSmokingen_ZA
dc.subjectOncogenesen_ZA
dc.titleSmoking, oncogenes and human lung cancer. A review of recent laboratory evidence linking smoking and lung canceren_ZA
dc.typeArticle
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