Non-allopathic adjuvant management of osteoarthritis by alkalinisation of the diet

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dc.contributor.authorVan Velden, David P.en_ZA
dc.contributor.authorReuter, Helmuthen_ZA
dc.contributor.authorKidd, Martinen_ZA
dc.contributor.authorMuller, F. Ottoen_ZA
dc.date.accessioned2016-09-22T13:44:26Z
dc.date.available2016-09-22T13:44:26Z
dc.date.issued2015
dc.descriptionCITATION: Van Velden, D. P., et al. 2015. Non-allopathic adjuvant management of osteoarthritis by alkalinisation of the diet. African Journal of Primary Health Care & Family Medicine, 7(1):1-7, doi:10.4102/phcfm.v7i1.780.
dc.descriptionThe original publication is available at http://www.phcfm.org
dc.description.abstractBackground: Osteoarthritis (OA) is a chronic condition. Nonsteroidal anti-inflammatory drugs recommended for treatment have serious adverse effects. A compelling body of anecdotal evidence alerted the authors to the therapeutic potential of dietary supplementation with Multiforce® (MF) Alkaline Powder for relief of OA symptoms. Aim: The aim of the study was to test the hypothesis that dietary supplementation with MF relieves clinical signs and symptoms of OA of the hands. Setting: The study was done at the MEDSAC hospital in Somerset West, Western Cape, South Africa. Methods: The research was conducted in two stages. An open interventional study (n = 40) confirmed the notion that MF 7.5 g twice daily is likely to be an effective alternative or adjunct for relief of symptoms of OA of the hands. The main study was conducted with 100 eligible, consenting volunteers (aged 47–89 years) according to a randomised, placebo-controlled, crossover design. Study duration was 56 days, 28 days per regimen; crossover to alternate regimens took place on day 28. Results: Compared to placebo, MF intake over 28 days was associated with significant reductions ( p < 0.005) in pain, tenderness and stiffness of interphalangeal and metacarpophalangeal joints of the hand. Confirmation of systemic alkalinisation by MF, which is rich in organic anions in the form of citrate salts, was reflected by a significant and sustained increase in urine pH. Conclusion: A dietary supplement, Multiforce® Alkaline Powder, containing citrate salts which are converted into bicarbonate in vivo, was efficacious and safe as sole therapeutic intervention, significantly attenuating OA-associated signs and symptoms of the hands.en_ZA
dc.description.urihttp://www.phcfm.org/index.php/phcfm/article/view/780
dc.description.versionPublisher's version
dc.format.extent7 pages
dc.identifier.citationVan Velden, D. P. 2015. Non-allopathic adjuvant management of osteoarthritis by alkalinisation of the diet. African Journal of Primary Health Care & Family Medicine, 7(1):1-7, doi:10.4102/phcfm.v7i1.780
dc.identifier.issn2071-2936 (online)
dc.identifier.issn2071-2928 (print)
dc.identifier.otherdoi:10.4102/phcfm.v7i1.780
dc.identifier.urihttp://hdl.handle.net/10019.1/99677
dc.language.isoen_ZAen_ZA
dc.publisherAOSIS Publishing
dc.rights.holderAuthors retain copyright
dc.subjectOsteoarthritis -- Diet therapyen_ZA
dc.subjectAlternative medicineen_ZA
dc.subjectAlkaline dieten_ZA
dc.titleNon-allopathic adjuvant management of osteoarthritis by alkalinisation of the dieten_ZA
dc.typeArticleen_ZA
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