Splenectomy in onyalai: A report on 5 cases

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dc.contributor.authorHesseling P.B.
dc.contributor.authorOosthuysen E.
dc.contributor.authorPretorius L.
dc.contributor.authorSwart, A.
dc.contributor.authorSteynberg, J.
dc.date.accessioned2011-03-18T14:59:44Z
dc.date.available2011-03-18T14:59:44Z
dc.date.issued1984
dc.descriptionArticle
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractOnyalai is an acquired immune thrombocytopenia with 10% mortality. Conservative measures such as traditional medicines, corticosteroids and blood transfusion have not always controlled severe bleeding or prevented death. Five patients (2 male, 3 female) with onyalai who had uncontrollable haemorrhage, thrombocytopenia and documented previous attacks of severe bleeding, underwent spleenectomy. The patients were screened for malaria, sickle-cell anaemia and bilharzia. Vitamin K and ε-aminocaproic acid was administered pre-operatively, and fresh blood was given during surgery. The duration of follow-up varied between 280 and 544 days. There were no operative complications. Bleeding stopped in all patients and platelet counts increased within 24 hours. All achieved normal platelet counts, but these were not always sustained. Three patients remained free of disease with normal platelet counts up to days 539, 539 and 544 of follow-up. Two patients had a recurrence of bleeding and died from cerebral haemorrhage and haemorrhagic shock.en_ZA
dc.description.versionPublishers’ versionen_ZA
dc.format.extentpp. 580-582 : ill.
dc.identifier.citationHesseling, P. B., E. Oosthuysen, Pretorius, L., Swart, A., Steynberg, J. 1984. Splenectomy in Onyalai: a report of 5 cases. South African Medical Journal, 66(10): 580-582.en_ZA
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/8018
dc.language.isoen_ZA
dc.publisherHealth and Medical Publishing Group (HMPG)en_ZA
dc.rights.holderThe authors retain copyright
dc.subjectAminocaproic aciden_ZA
dc.subjectMenadioneen_ZA
dc.subjectBlood and hemopoietic systemen_ZA
dc.subjectBlood transfusionsen_ZA
dc.subjectOnyalai -- Etiology -- Namibia -- Kavango -- Case studiesen_ZA
dc.subjectDiseases -- Causes and theories of causationen_ZA
dc.subjectSpleen -- Diseases -- Diagnosis -- Namibia -- Kavango -- Case studiesen_ZA
dc.subjectSplenectomyen_ZA
dc.subjectAcquired immune thrombocytopenia -- Namibia -- Kavango -- Case studiesen_ZA
dc.subjectSleen -- Diseases -- Treatment -- Namibia -- Kavangoen_ZA
dc.titleSplenectomy in onyalai: A report on 5 casesen_ZA
dc.typeArticleen_ZA
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