Immunoreactive digitalis-like substance in pre-eclampsia
| dc.contributor.author | Odendaal, H. J. | en_ZA |
| dc.contributor.author | Beyers, A. D. | en_ZA |
| dc.contributor.author | Van Heyningen, C. F. | en_ZA |
| dc.contributor.author | Spruyt, L. L. | en_ZA |
| dc.contributor.author | Kotze, T. J. van W. | en_ZA |
| dc.contributor.author | Van Jaarsveld, P. P. | en_ZA |
| dc.date.accessioned | 2011-03-18T14:57:31Z | |
| dc.date.available | 2011-03-18T14:57:31Z | |
| dc.date.issued | 1986 | |
| dc.description | CITATION: Odendaal, H. J. 1986. Immunoreactive digitalis-like substance in pre-eclampsia. South African Medical Journal, 70:535-537. | |
| dc.description | The original publication is available at http://www.samj.org.za | |
| dc.description.abstract | An endogenous digitalis-like substance (DLS) may be involved in the pathogenesis of essential hypertension and pre-eclampsia. The digoxin levels in maternal and cord blood of 504 randomly selected patients were determined. Since none of the patients received digoxin, these levels indicated a cross-reacting substance (immunoreactive DLS). DLS levels were significantly higher in the cord blood of pre-eclamptic patients than in the cord blood of controls. DLS levels in cord blood increased with the severity of pre-eclampsia, and levels were higher in primigravidas than in multigravidas. The structure and biological activity of DLS must be determined before definite conclusions about its role in the pathogenesis of pre-eclampsia can be made. | |
| dc.description.version | Publisher’s version | |
| dc.format.extent | 3 pages | |
| dc.identifier.issn | 2078-5135 (online) | |
| dc.identifier.issn | 0256-9574 (print) | |
| dc.identifier.uri | http://hdl.handle.net/10019.1/7467 | |
| dc.language.iso | en | |
| dc.publisher | Health & Medical Publishing Group | |
| dc.rights.holder | South African Medical Journal | |
| dc.subject | Preeclampsia | en_ZA |
| dc.title | Immunoreactive digitalis-like substance in pre-eclampsia | en_ZA |
| dc.type | Article |
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