Renal denervation : mechanisms and clinical aspects

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dc.contributor.authorHeradien, Marshall J.en_ZA
dc.contributor.authorVan Der Bijl, Pieteren_ZA
dc.contributor.authorBrink, Paul A.en_ZA
dc.date.accessioned2020-04-27T20:27:24Z
dc.date.available2020-04-27T20:27:24Z
dc.date.issued2020
dc.descriptionCITATION: Heradien, M. J., Van Der Bijl, P. & Brink, P. A. 2020. Renal denervation : mechanisms and clinical aspects. African Journal of Nephrology, 23(1):19-24, doi:10.21804/23-1-3974.
dc.descriptionThe original publication is available at http://www.journals.ac.za/index.php/ajn/
dc.description.abstractENGLISH ABSTRACT: Hypertension is a global health issue of paramount importance, which has not spared the African continent where an unacceptably high prevalence of uncontrolled blood pressure prevails among its population. Renal denervation (RD) represents an invasive management option for resistant hypertension, acting via several different physiological pathways – mostly predicated on modification of the renal autonomic nervous system. The evidence base for RD has recently been expanded by three randomised, sham-controlled clinical trials, which demonstrated significant blood pressure reductions under a variety of clinical conditions. In this review, both the renal mechanisms underlying RD, as well as the clinical aspects of its application to hypertension, are discussed.en_ZA
dc.description.urihttps://www.journals.ac.za/index.php/ajn/article/view/3974
dc.description.versionPublisher's version
dc.format.extent6 pagesen_ZA
dc.identifier.citationHeradien, M. J., Van Der Bijl, P. & Brink, P. A. 2020. Renal denervation : mechanisms and clinical aspects. African Journal of Nephrology, 23(1):19-24, doi:10.21804/23-1-3974
dc.identifier.issn2518-4601 (online)
dc.identifier.issn2306-8205 (print)
dc.identifier.otherdoi:10.21804/23-1-3974
dc.identifier.urihttp://hdl.handle.net/10019.1/107733
dc.language.isoen_ZAen_ZA
dc.publisherAfrican Association of Nephrologyen_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectHypertensionen_ZA
dc.subjectRenal denervationen_ZA
dc.subjectAfricaen_ZA
dc.subjectAfferent pathwaysen_ ZA
dc.titleRenal denervation : mechanisms and clinical aspectsen_ZA
dc.typeArticleen_ZA
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