Animal-adapted members of the Mycobacterium tuberculosis complex endemic to the southern African subregion

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dc.contributor.authorClarke, Charleneen_ZA
dc.contributor.authorVan Helden, Paulen_ZA
dc.contributor.authorMiller, Michele Annen_ZA
dc.contributor.authorParsons, Svenen_ZA
dc.date.accessioned2016-10-20T07:16:33Z
dc.date.available2016-10-20T07:16:33Z
dc.date.issued2016-04en_ZA
dc.descriptionCITATION: Clarke, C., Van Helden, P., Miller, M. & Parsons, S. 2016. Animal-adapted members of the Mycobacterium tuberculosis complex endemic to the southern African subregion. Journal of the South African Veterinary Association, 87(1), a1322, doi:10.4102/jsava.v87i1.1322.en_ZA
dc.descriptionThe original publication is available at http://www.jsava.co.za
dc.description.abstractMembers of the Mycobacterium tuberculosis complex (MTC) cause tuberculosis (TB) in both animals and humans. In this article, three animal-adapted MTC strains that are endemic to the southern African subregion – that is, Mycobacterium suricattae, Mycobacterium mungi, and the dassie bacillus – are reviewed with a focus on clinical and pathological presentations, geographic distribution, genotyping methods, diagnostic tools and evolution. Moreover, factors influencing the transmission and establishment of TB pathogens in novel host populations, including ecological, immunological and genetic factors of both the host and pathogen, are discussed. The risks associated with these infections are currently unknown and further studies will be required for greater understanding of this disease in the context of the southern African ecosystem.en_ZA
dc.description.urihttp://www.jsava.co.za/index.php/jsava/article/view/1322
dc.description.versionPublisher's version
dc.format.extent7 pagesen_ZA
dc.identifier.citationClarke, C., Van Helden, P., Miller, M. & Parsons, S. 2016. Animal-adapted members of the Mycobacterium tuberculosis complex endemic to the southern African subregion. Journal of the South African Veterinary Association, 87(1), a1322, doi:10.4102/jsava.v87i1.1322.en_ZA
dc.identifier.issn2224-9435 (online)
dc.identifier.issn1019-9128 (print)
dc.identifier.otherdoi:10.4102/jsava.v87i1.1322
dc.identifier.urihttp://hdl.handle.net/10019.1/99737
dc.language.isoen_ZAen_ZA
dc.publisherAOSIS Publishing
dc.rights.holderAuthors retain copyright
dc.subjectNatural immunityen_ZA
dc.subjectMycobacterium bovisen_ZA
dc.subjectMycobacterium tuberculosis -- Southern African subregionen_ZA
dc.subjectPhylogenyen_ZA
dc.subjectMycobacterial diseasesen_ZA
dc.titleAnimal-adapted members of the Mycobacterium tuberculosis complex endemic to the southern African subregionen_ZA
dc.typeArticleen_ZA
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