Lung volume reduction in chronic obstructive pulmonary disease

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dc.contributor.authorVorster, M. J.en_ZA
dc.contributor.authorKoegelenberg, C. F. N.en_ZA
dc.date.accessioned2016-07-29T06:29:52Z
dc.date.available2016-07-29T06:29:52Z
dc.date.issued2015
dc.descriptionCITATION: Vorster, M. J. & Koegelenberg, C. F. N. 2015. Lung volume reduction in chronic obstructive pulmonary disease. South African Medical Journal, 105(9):791-793, doi:10.7196/SAMJnew.8427.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractPathognomonic features of advanced emphysema include a markedly reduced alveolar surface area due to the formation of blebs and bullae and significantly reduced elastic recoil. The aim of lung volume reduction, which can be achieved by either surgery or endoscopic techniques, is volume loss of the targeted, diseased region(s) and redirecting airflow to less affected regions. Lung volume reduction surgery (LVRS) entails reducing the lung volume by wedge excision of emphysematous tissue. LVRS carries significant morbidity and mortality, but can offer survival benefit and increased exercise capacity in selected patients with predominantly upper-lobe emphysema and low exercise capacity. Endoscopic lung volume reduction (ELVR) refers to bronchoscopically inducing volume loss to improve pulmonary mechanics and compliance, thereby reducing the work of breathing. Globally, this technique is increasingly used as treatment for advanced emphysema with the objective of obtaining similar functional advantages to surgical lung volume reduction, while decreasing risks and costs. Current evidence suggests that patients with either homogeneous or heterogeneous disease may benefit from ELVR. It remains paramount that a systematic approach is followed and selection criteria are met, given the high costs and potential complications related to both LVRS and ELVR.en_ZA
dc.description.abstractAFRIKAANSE OPSOMMING: Geen opsomming beskikbaaraf_ZA
dc.description.urihttp://www.samj.org.za/index.php/samj/article/view/9976
dc.description.versionPublisher's version
dc.format.extent3 pages : illustrationsen_ZA
dc.identifier.citationVorster, M. J. & Koegelenberg, C. F. N. 2015. Lung volume reduction in chronic obstructive pulmonary disease. South African Medical Journal, 105(9):791-793, doi:10.7196/SAMJnew.8427
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.otherdoi:10.7196/SAMJnew.8427
dc.identifier.urihttp://hdl.handle.net/10019.1/99271
dc.language.isoen_ZAen_ZA
dc.publisherHealth & Medical Publishing Groupen_ZA
dc.rights.holderHealth & Medical Publishing Groupen_ZA
dc.subjectPulmonary diseasesen_ZA
dc.subjectObstructive lung diseasesen_ZA
dc.subjectEndoscopic surgeryen_ZA
dc.titleLung volume reduction in chronic obstructive pulmonary diseaseen_ZA
dc.typeArticleen_ZA
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