Hypoosmotic swelling test in the prediction of male fertility

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dc.contributor.authorCoetzee K.
dc.contributor.authorKruger T.F.
dc.contributor.authorMenkveld R.
dc.contributor.authorLombard C.J.
dc.contributor.authorSwanson R.J.
dc.date.accessioned2011-05-15T16:15:36Z
dc.date.available2011-05-15T16:15:36Z
dc.date.issued1989
dc.description.abstractThe hypoosmotic swelling test (HOS) is a simple test to measure the functional competence of human sperm membranes. The question is, does a relationship exist between this competence and the fertilization potential of human spermatozoa? In this study the strongest correlation (r = 0.76) was obtained between sperm swelling and sperm viability (supravital staining). Only a moderate correlation (r = 0.50) was obtained with normal sperm morphology; weaker correlations were also obtained with the sperm penetration assay (r = 0.42) and human IVF (r = 0.24). The results, therefore, indicate that the HOS test has a limited predictive value. Notwithstanding this low concordance between sperm swelling and fertilizing potential, a <50% HOS test threshold was seen to be a definite indicator of a male factor.
dc.description.versionArticle
dc.identifier.citationArchives of Andrology
dc.identifier.citation23
dc.identifier.citation2
dc.identifier.issn01485016
dc.identifier.urihttp://hdl.handle.net/10019.1/13406
dc.subjectcell culture
dc.subjectcell volume
dc.subjectcontrolled study
dc.subjectfertilization in vitro
dc.subjecthuman cell
dc.subjectinfertility
dc.subjectmale
dc.subjectmethodology
dc.subjectnormal human
dc.subjectosmoregulation
dc.subjectpriority journal
dc.subjectspermatozoon
dc.subjectCell Survival
dc.subjectFemale
dc.subjectFertility
dc.subjectHuman
dc.subjectMale
dc.subjectOsmolar Concentration
dc.subjectSperm-Ovum Interactions
dc.subjectSpermatozoa
dc.titleHypoosmotic swelling test in the prediction of male fertility
dc.typeArticle
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