The Vaccine and Cervical Cancer Screen project 2 (VACCS 2) : linking cervical cancer screening to a two-dose HPV vaccination schedule in the South-West District of Tshwane, Gauteng, South Africa
| dc.contributor.author | Snyman, Leon C. | en_ZA |
| dc.contributor.author | Greta, Dreyer | en_ZA |
| dc.contributor.author | Visser, Cathy | en_ZA |
| dc.contributor.author | Botha, Matthys H. | en_ZA |
| dc.contributor.author | Van der Merwe, Frederick H. | en_ZA |
| dc.date.accessioned | 2016-08-11T10:25:50Z | |
| dc.date.available | 2016-08-11T10:25:50Z | |
| dc.date.issued | 2015 | |
| dc.description | CITATION: Snyman, L. C., et al. 2015. The Vaccine and Cervical Cancer Screen project 2 (VACCS 2) : linking cervical cancer screening to a two-dose HPV vaccination schedule in the South-West District of Tshwane, Gauteng, South Africa. South African Medical Journal, 105(3):191-194, doi:10.7196/SAMJ.8888. | |
| dc.description | The original publication is available at http://www.samj.org.za | |
| dc.description.abstract | Background. Cervical cancer is a preventable disease with a high prevalence in South Africa (SA), where screening is opportunistic. Primary prevention is now possible through HPV vaccination. In VACCS 1 the feasibility of linking cervical cancer with HPV vaccination was demonstrated. Objectives. To investigate the feasibility of linking HPV self-testing with a two-dose HPV vaccination schedule and to compare results with VACCS 1. Methods. The project was conducted in five schools in the South-West District of Tshwane, Gauteng, SA. Leaflet information on cervical cancer and screening was provided, with requests for consent and assent for a two-dose HPV vaccination of schoolgirls. Female caregivers were invited to take part in HPV self-screening. Results. Of 965 girls invited for vaccination, 519 (53.7%) had full consent and 518 (99.8%) received at least one vaccine dose. The invited uptake rate was 53.7% and 495 girls received both doses, giving a completion rate of 95.4% v. 82.6% in VACCS 1. Of 1 135 self-screen kits handed out, 560 (49.3%) were not returned. The mean age (standard deviation) of the 160 women who participated in self-screening was 38.7 (7.7) years. HPV testing was negative in 116 women (72.5%), 15 women (9.4%) tested positive for HPV 16 and/or 18, and 27 (16.9%) were positive for non-16/18 oncogenic HPV. Conclusion. Data from the VACCS projects suggest that school-based vaccine programmes can be successfully implemented. A two-dose schedule allowed for higher completion rates. Linking self-collected HPV screening to HPV vaccination is feasible, is a promising and viable screening strategy, and reached the appropriate age group for screening. | en_ZA |
| dc.description.abstract | AFRIKAANSE OPSOMMING: Geen opsomming beskikbaar | af_ZA |
| dc.description.uri | http://www.samj.org.za/index.php/samj/article/view/8888/ | |
| dc.description.version | Publisher's version | |
| dc.format.extent | 4 pages | en_ZA |
| dc.identifier.citation | Snyman, L. C., et al. 2015. The Vaccine and Cervical Cancer Screen project 2 (VACCS 2) : linking cervical cancer screening to a two-dose HPV vaccination schedule in the South-West District of Tshwane, Gauteng, South Africa. South African Medical Journal, 105(3):191-194, doi:10.7196/SAMJ.8888 | |
| dc.identifier.issn | 2078-5135 (online) | |
| dc.identifier.issn | 0256-9574 (print) | |
| dc.identifier.other | doi:10.7196/SAMJ.8888 | |
| dc.identifier.uri | http://hdl.handle.net/10019.1/99358 | |
| dc.language.iso | en_ZA | en_ZA |
| dc.publisher | Health and Medical Publishing Group | en_ZA |
| dc.rights.holder | Health & Medical Publishing Group | en_ZA |
| dc.subject | Cervical cancer -- Prevention | en_ZA |
| dc.subject | Papillomavirus vaccines | en_ZA |
| dc.subject | Medical screening | en_ZA |
| dc.title | The Vaccine and Cervical Cancer Screen project 2 (VACCS 2) : linking cervical cancer screening to a two-dose HPV vaccination schedule in the South-West District of Tshwane, Gauteng, South Africa | en_ZA |
| dc.type | Article | en_ZA |