Localized basal meningeal enhancement in tuberculous meningitis

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dc.contributor.authorTheron S.
dc.contributor.authorAndronikou S.
dc.contributor.authorGrobbelaar M.
dc.contributor.authorSteyn F.
dc.contributor.authorMapukata A.
dc.contributor.authordu Plessis J.
dc.date.accessioned2011-05-15T16:17:42Z
dc.date.available2011-05-15T16:17:42Z
dc.date.issued2006
dc.description.abstractBackground: Focal basal meningeal enhancement may produce a confusing CT picture in children with suspected tuberculous meningitis (TBM). Objective: To demonstrate the incidence, distribution and appearance of localized basal meningeal enhancement in children with TBM. Materials and methods: CT scans of patients with definite (culture proven) and probable (CSF suggestive) TBM were retrospectively evaluated by two observers. Localized basal enhancement was documented as involving: unilateral cistern of the lateral fossa (CLF), unilateral sylvian fissure, unilateral CLF and sylvian fissure in combination, unilateral CLF and sylvian fissure with ipsi- or contralateral ambient cistern and isolated quadrigeminal plate cistern. Results: The study included 130 patients with TBM (aged 2 months to 13 years 9 months). Focal basal enhancement was seen in 11 patients (8.5%). The sylvian fissure was involved most commonly, followed by the lateral fossa cistern. The ambient cistern was involved in three patients and the quadrigeminal plate cistern in one. Focal areas of enhancement corresponded to the areas of infarction in every patient. Conclusion: Focal basal meningeal enhancement is common (8.5%) in paediatric TBM. This must be kept in mind when evaluating CT scans in children presenting with focal neurological findings, seizures or meningism in communities where TBM is endemic. © Springer-Verlag 2006.
dc.description.versionArticle
dc.identifier.citationPediatric Radiology
dc.identifier.citation36
dc.identifier.citation11
dc.identifier.issn03010449
dc.identifier.other10.1007/s00247-006-0312-1
dc.identifier.urihttp://hdl.handle.net/10019.1/14334
dc.subjectarticle
dc.subjectbrain infarction
dc.subjectbrain scintiscanning
dc.subjectcerebrospinal fluid culture
dc.subjectchild
dc.subjectclinical article
dc.subjectcomputer assisted tomography
dc.subjectcontrast enhancement
dc.subjectcontrolled study
dc.subjectculture technique
dc.subjectfemale
dc.subjecthuman
dc.subjectincidence
dc.subjectmale
dc.subjectmedical record review
dc.subjectpriority journal
dc.subjecttuberculous meningitis
dc.subjectAdolescent
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectFemale
dc.subjectHumans
dc.subjectInfant
dc.subjectInfant, Newborn
dc.subjectMale
dc.subjectMeninges
dc.subjectRadiographic Image Enhancement
dc.subjectRetrospective Studies
dc.subjectTomography, X-Ray Computed
dc.subjectTuberculosis, Meningeal
dc.titleLocalized basal meningeal enhancement in tuberculous meningitis
dc.typeArticle
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