Aetiopathogenesis of atopic dermatitis

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dc.contributor.authorJordaan, H. F.en_ZA
dc.contributor.authorTodd, G.en_ZA
dc.contributor.authorSinclair, W.en_ZA
dc.contributor.authorGreen, R. J.en_ZA
dc.date.accessioned2015-12-10T08:54:27Z
dc.date.available2015-12-10T08:54:27Z
dc.date.issued2014-10
dc.descriptionCITATION: Jordaan, H. F., Todd, G., Sinclair, W. & Green, R. J. 2014. Aetiopathogenesis of atopic dermatitis. South African Medical Journal, 104(10):706-709, doi:10.7196/SAMJ.8840.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractThe aetiopathogenesis of atopic dermatitis (AD) is complex and during recent years much has been learnt regarding the genetic predisposition to the development of this condition and how its interaction with the environment influences clinical manifestations. AD is not a simple allergic condition. An inherited stratum corneum barrier defect, transepidermal water loss, early antigen exposure through the skin and over-hygienic care of the young child seem to be the major drivers in the manifestation of the disease. Many other, more specific, environmental factors may influence the clinical picture in individual patients; some of these have an allergic basis, while others do not. In this article, the terminology used in this issue of CME is explained, the evidence for the different aetiopathological factors is presented and the factors that worsen or improve AD are listed.en_ZA
dc.description.urihttp://www.samj.org.za/index.php/samj/article/view/8840
dc.description.versionPublisher's version
dc.format.extent4 pages
dc.identifier.citationJordaan, H. F., Todd, G., Sinclair, W. & Green, R. J. 2014. Aetiopathogenesis of atopic dermatitis. South African Medical Journal, 104(10):706-709, doi:10.7196/SAMJ.8840.
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.otherdoi:10.7196/SAMJ.8840
dc.identifier.urihttp://hdl.handle.net/10019.1/97676
dc.language.isoen_ZAen_ZA
dc.publisherHealth & Medical Publishing Group
dc.rights.holderSouth African Medical Journal
dc.subjectAtopic dermatitisen_ZA
dc.titleAetiopathogenesis of atopic dermatitisen_ZA
dc.typeArticleen_ZA
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