Antiretroviral therapy for the management of HIV in children

dc.contributor.authorFrigati, L.en_ZA
dc.contributor.authorCotton, Mark F.en_ZA
dc.contributor.authorRabie, H.en_ZA
dc.date.accessioned2016-01-13T09:17:07Z
dc.date.available2016-01-13T09:17:07Z
dc.date.issued2014-12
dc.descriptionPlease cite as follows: Frigati, L., Cotton, M. & Rabie, H. 2014. Antiretroviral therapy for the management of HIV in children. South African Medical Journal, 104(12):898, doi:10.7196/SAMJ.9091.en_ZA
dc.descriptionThe original publication is available at http://www.samj.org.zaen_ZA
dc.description.abstractSince 2004, when antiretroviral therapy (ART) was first available to children through the National Department of Health, there has been significant progress in preventing and treating paediatric HIV. Large cohort studies and prospective trials confirmed that young children require early diagnosis with rapid access to ART regardless of CD4+ lymphocyte count. Studies also confirmed the importance of ritonavir-boosted protease inhibitors during therapy, regardless of prior nevirapine exposure. As prevention strengthens and the paediatric population ages, the goal posts are shifting towards even earlier diagnosis, targeting newborn infants on the first day of life and also the perinatally infected adolescent. There is an increasing focus on the long-term health, social, developmental and scholastic outcomes of HIV-infected children. Clinicians require new skills to assist children with transition into adulthood. In this article we focus on the care of infants and children.en_ZA
dc.description.urihttp://www.samj.org.za/index.php/samj/article/view/9091
dc.description.versionPublisher's versionen_ZA
dc.format.extent4 pagesen_ZA
dc.identifier.citationFrigati, L., Cotton, M. & Rabie, H. 2014. Antiretroviral therapy for the management of HIV in children. South African Medical Journal, 104(12):898, doi:10.7196/SAMJ.9091.en_ZA
dc.identifier.issn0256-9574 (print)
dc.identifier.issn2078-5135 (online)
dc.identifier.otherdoi:10.7196/SAMJ.9091
dc.identifier.urihttp://hdl.handle.net/10019.1/98157
dc.language.isoen_ZAen_ZA
dc.publisherHealth & Medical Publishing Groupen_ZA
dc.rights.holderSouth African Medical Journalen_ZA
dc.subjectHighly active antiretroviral therapyen_ZA
dc.subjectHIV-positive childrenen_ZA
dc.subjectHIV infections -- Treatmenten_ZA
dc.subjectAIDS (Disease) in children -- Treatmenten_ZA
dc.subjectAntiretroviral agentsen_ZA
dc.titleAntiretroviral therapy for the management of HIV in childrenen_ZA
dc.typeArticleen_ZA
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