Patients' motivations for participating in cardiovascular clinical trials: A local perspective

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dc.contributor.authorBurgess L.J.
dc.contributor.authorSulzer N.U.
dc.contributor.authorHoosain F.
dc.contributor.authorLeverton N.
dc.contributor.authorBliganut S.
dc.contributor.authorEmanuel S.
dc.date.accessioned2011-05-15T16:15:52Z
dc.date.available2011-05-15T16:15:52Z
dc.date.issued2009
dc.description.abstractObjective: To investigate patients' motivations for participating in cardiovascular clinical trials. Methods: Patients attending TREAD Research, located within Tygerberg Hospital, Parow, Western Cape, between January 2005 and May 2006 were approached to participate in the study. Consenting patients were given a validated questionnaire to complete in their home language. All questionnaires were anonymous and 250 consecutive patients completed the questionnaire. They provided basic demographic data and rated their response to 18 statements concerning factors that may or may not have influenced their decision to participate in a clinical trial. Results: The mean (± SD) age of subjects was 56.3 ± 10.9 years. A large percentage of the respondents were unemployed (66.5%). Access to medical care was a motivation for the majority of patients (90.5%). Ninety-six per cent of patients appreciated the regular follow up they received as trial participants; 90% of patients entered the trial to receive medication, which they could otherwise not afford. A substantial 98% of patients participated to learn more about their disease. Almost all (99%) wanted to further the scientific understanding of their condition. A reassuring 94% of subjects felt that they were not pressurised into the study; 80% of patients disagreed that participation in clinical trials was an easy way to obtain money. Conclusions: Access to medical care and making a contribution to scientific knowledge are two of the most common motivations for participation in cardiovascular clinical trials. The role of remuneration is relatively unimportant.
dc.description.versionArticle
dc.identifier.citationCardiovascular Journal of Africa
dc.identifier.citation20
dc.identifier.citation4
dc.identifier.issn19951892
dc.identifier.urihttp://hdl.handle.net/10019.1/13529
dc.subjectadult
dc.subjectaged
dc.subjectarticle
dc.subjectclinical research
dc.subjectdemography
dc.subjectfemale
dc.subjecthealth care access
dc.subjecthealth survey
dc.subjecthuman
dc.subjectinformed consent
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmoney
dc.subjectmotivation
dc.subjectpatient decision making
dc.subjectpatient participation
dc.subjectquestionnaire
dc.subjectresearch subject
dc.subjectSouth Africa
dc.subjectAdult
dc.subjectClinical Trials as Topic
dc.subjectFemale
dc.subjectHealth Education
dc.subjectHealth Services Accessibility
dc.subjectHumans
dc.subjectMale
dc.subjectMotivation
dc.subjectPatient Selection
dc.subjectPatients
dc.subjectQuestionnaires
dc.titlePatients' motivations for participating in cardiovascular clinical trials: A local perspective
dc.typeArticle
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