A comparison of heart rate variability in affected and unaffected members of families with progressive familial heart block type I

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dc.contributor.authorVan Der Merwe P.-L.
dc.contributor.authorWeymar H.W.
dc.contributor.authorKalis N.N.
dc.date.accessioned2011-05-15T16:15:59Z
dc.date.available2011-05-15T16:15:59Z
dc.date.issued1994
dc.description.abstractThe presence of sinus bradycardia (less than 60/min) in patients affected by progressive familial heart block type I (PFHB1) and their inability to reach a target heart rate during exercise testing, prompted an investigation of the influence of the autonomic nervous system on cardiac conduction in these family members. Forty members of PFHB1 families, 20 affected and 20 not affected, were included in the study. All were subjected to 24-hour Holter monitoring and treadmill exercise testing (Bruce protocol). Spectral and non-spectral analyses of heart rate variability were performed to evaluate the autonomic nervous system. The results showed that there were no differences between the two groups and that they had normal autonomic nervous systems. It is therefore possible to conclude that the slow heart rate at rest of affected PFHB1 family members and their inability to reach a target heart rate during exercise testing is due to a primarily diseased heart conduction system.
dc.description.versionArticle
dc.identifier.citationCardiovascular Journal of Southern Africa
dc.identifier.citation5
dc.identifier.citation1
dc.identifier.issn10159657
dc.identifier.urihttp://hdl.handle.net/10019.1/13584
dc.subjectadult
dc.subjectarticle
dc.subjectclinical article
dc.subjectcontrolled study
dc.subjectfamilial disease
dc.subjectfemale
dc.subjectheart block
dc.subjecthuman
dc.subjectmale
dc.subjectsinus bradycardia
dc.titleA comparison of heart rate variability in affected and unaffected members of families with progressive familial heart block type I
dc.typeArticle
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