Distal malignant biliary obstruction : a prospective randomised trial comparing plastic and uncovered self-expanding metal stents in the palliation of symptomatic jaundice

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dc.contributor.authorBernon, M. M.en_ZA
dc.contributor.authorShaw, J.en_ZA
dc.contributor.authorBurmeister, S.en_ZA
dc.contributor.authorChinnery, G.en_ZA
dc.contributor.authorHofmeyr, S.en_ZA
dc.contributor.authorKloppers, J. C.en_ZA
dc.contributor.authorJonas, E.en_ZA
dc.contributor.authorKrige, J. E. J.en_ZA
dc.date.accessioned2020-03-05T07:57:40Z
dc.date.available2020-03-05T07:57:40Z
dc.date.issued2018
dc.descriptionCITATION: Bernon, M. M., et al. 2018. Distal malignant biliary obstruction : a prospective randomised trial comparing plastic and uncovered self-expanding metal stents in the palliation of symptomatic jaundice. South African Journal of Surgery, 56(1):30-34, doi:10.17159/2078-5151/2018/v56n1a2208.
dc.descriptionThe original publication is available at http://www.scielo.org.za
dc.description.abstractBackground: The aim of this study was to determine the safety and clinical effectiveness of 10Fr plastic biliary stents compared to uncovered self-expanding metal stents (SEMS) for palliative treatment of patients with inoperable extra-hepatic malignant biliary obstruction in a public hospital in South Africa. Methods: From January 2009 to December 2013, 40 patients who were admitted to a tertiary academic centre because of distal malignant biliary obstruction were enrolled in a prospective randomized study. Patients were randomly assigned to receive an uncovered SEMS or a plastic stent deployed through the biliary stricture during endoscopic retrograde cholangiopancreatography (ERCP). Results: Patient survival time in the two groups did not differ significantly (median: SEMS – 114 days; plastic – 107 days). Stent failure was more common in the plastic stent group (7/19 vs. 1/21). The results became significant after 6 months of follow-up. There was no significant difference between the two groups in the incidence of serious adverse events. Conclusions: SEMS had a longer duration of patency than plastic stents, which recommends their use in the palliative treatment of patients with biliary obstruction due to distal malignant biliary obstruction.en_ZA
dc.description.urihttp://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0038-23612018000100006&lng=en&nrm=iso&tlng=en
dc.description.versionPublishers versionen_ZA
dc.format.extent5 pagesen_ZA
dc.identifier.citationBernon, M. M., et al. 2018. Distal malignant biliary obstruction : a prospective randomised trial comparing plastic and uncovered self-expanding metal stents in the palliation of symptomatic jaundice. South African Journal of Surgery, 56(1):30-34, doi:10.17159/2078-5151/2018/v56n1a2208
dc.identifier.issn2078-5151 (online)
dc.identifier.issn0038-2361 (print)
dc.identifier.otherdoi:10.17159/2078-5151/2018/v56n1a2208
dc.identifier.urihttp://hdl.handle.net/10019.1/107584
dc.language.isoen_ZAen_ZA
dc.publisherHealth and Medical Publishing Groupen_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectSelf-expanding metal stentsen_ZA
dc.subjectPalliative treatmenten_ZA
dc.subjectJaundice -- Signs, Clinicalen_ZA
dc.subjectBiliary tract -- Canceren_ZA
dc.titleDistal malignant biliary obstruction : a prospective randomised trial comparing plastic and uncovered self-expanding metal stents in the palliation of symptomatic jaundiceen_ZA
dc.typeArticleen_ZA
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