Proximal renal tubular acidosis in pregnancy: A case report and literature review

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dc.contributor.authorFirmin C.J.
dc.contributor.authorKruger T.F.
dc.contributor.authorDavids, MR
dc.date.accessioned2011-05-15T16:16:29Z
dc.date.available2011-05-15T16:16:29Z
dc.date.issued2007
dc.description.abstractRenal tubular acidosis is usually associated with chronic renal conditions and is rarely encountered in pregnancy. It may be inherited causing osteomalacia and rickets in children or acquired following autoimmune diseases or following exposure to nephrotoxic agents. It is known to worsen during pregnancy and if left untreated may cause maternal and foetal morbidity or death. We report a 28-year-old woman, gravida 3 para 2, who presented at 30 weeks gestation with lethargy, weakness and generalized myalgia. Investigation revealed severe hypokalaemia and a systemic metabolic acidosis due to proximal renal tubular acidosis. Her previous pregnancies were both complicated by foetal losses at term. Following prompt correction of her electrolyte disturbance and metabolic acidosis, she went on to deliver a healthy female infant at term. Regular evaluation up to 1 year post-partum revealed mild persistence of her hypokalaemia. At 1 year, the infant showed no signs of the disorder and is growing normally. Copyright © 2007 S. Karger AG.
dc.description.versionArticle
dc.identifier.citationGynecologic and Obstetric Investigation
dc.identifier.citation63
dc.identifier.citation1
dc.identifier.issn03787346
dc.identifier.other10.1159/000094942
dc.identifier.urihttp://hdl.handle.net/10019.1/13802
dc.subjectbicarbonate
dc.subjectmedroxyprogesterone acetate
dc.subjectnitrofurantoin
dc.subjectpotassium
dc.subjectpotassium chloride
dc.subjectadult
dc.subjectarticle
dc.subjectcase report
dc.subjectdisease severity
dc.subjectelectrolyte disturbance
dc.subjectfemale
dc.subjecthuman
dc.subjecthypokalemia
dc.subjectkidney tubule acidosis
dc.subjectlaboratory test
dc.subjectmetabolic disorder
dc.subjectpregnancy
dc.subjectpriority journal
dc.subjecturinary tract infection
dc.subjectAcidosis, Renal Tubular
dc.subjectAdult
dc.subjectFemale
dc.subjectHumans
dc.subjectHypokalemia
dc.subjectPregnancy
dc.subjectPregnancy Complications
dc.titleProximal renal tubular acidosis in pregnancy: A case report and literature review
dc.typeArticle
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