Molecular detection of airborne Emergomyces africanus, a thermally dimorphic fungal pathogen, in Cape Town, South Africa

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dc.contributor.authorSchwartz, Ilan S.en_ZA
dc.contributor.authorMcLoud, Josh D.en_ZA
dc.contributor.authorBerman, Dilysen_ZA
dc.contributor.authorBotha, Alfreden_ZA
dc.contributor.authorLerm, Barbraen_ZA
dc.contributor.authorColebunders, Roberten_ZA
dc.contributor.authorLevetin, Estelleen_ZA
dc.contributor.authorKenyon, Chrisen_ZA
dc.date.accessioned2020-05-15T14:58:24Z
dc.date.available2020-05-15T14:58:24Z
dc.date.issued2018
dc.descriptionCITTION: Schwartz, I. S., et al. 2018. Molecular detection of airborne Emergomyces africanus, a thermally dimorphic fungal pathogen, in Cape Town, South Africa. PLOS Neglected Tropical Diseases, 12(1):e0006174, doi:10.1371/journal.pntd.0006174.
dc.descriptionThe original publication is available at https://journals.plos.org/plosntds
dc.description.abstractEmergomyces africanus is a thermally dimorphic fungus that causes a systemic mycosis in immunocompromised persons in South Africa. Infection is presumed to follow inhalation of airborne propagules. We developed a quantitative PCR protocol able to detect as few as 5 Es. africanus propagules per day. Samples were collected in Cape Town, South Africa over 50 weeks by a Burkard spore trap with an alternate orifice. We detected Es. africanus in air samples from 34 days (10%) distributed over 11 weeks. These results suggest environmental exposure to airborne Es. africanus propagules occurs more commonly in endemic areas than previously appreciated.en_ZA
dc.description.urihttps://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0006174
dc.description.versionPublisher's version
dc.format.extent12 pages
dc.identifier.citationSchwartz, I. S., et al. 2018. Molecular detection of airborne Emergomyces africanus, a thermally dimorphic fungal pathogen, in Cape Town, South Africa. PLOS Neglected Tropical Diseases, 12(1):e0006174, doi:10.1371/journal.pntd.0006174
dc.identifier.issn1935-2735 (online)
dc.identifier.issn1935-2727 (print)
dc.identifier.otherdoi:10.1371/journal.pntd.0006174
dc.identifier.urihttp://hdl.handle.net/10019.1/108560
dc.language.isoen_ZAen_ZA
dc.publisherPublic Library of Science
dc.rights.holderAuthors retain copyright
dc.subjectEmergomyces africanus -- Detection -- South Africa -- Cape Townen_ZA
dc.subjectAirborne infection -- Detectionen_ZA
dc.subjectPathogenic microorganisms -- Detectionen_ZA
dc.subjectThermally dimorphic fungien_ZA
dc.subjectSystemic mycosesen_ZA
dc.titleMolecular detection of airborne Emergomyces africanus, a thermally dimorphic fungal pathogen, in Cape Town, South Africaen_ZA
dc.typeArticleen_ZA
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