Clinical determinants distinguishing communicating and non-communicating hydrocephalus in childhood tuberculous meningitis at presentation

dc.contributor.advisorSolomons, Regan
dc.contributor.advisorVan Toorn, Ronald
dc.contributor.authorBovula, Siyabulela
dc.date.accessioned2023-01-26T06:42:29Z
dc.date.available2023-01-26T06:42:29Z
dc.date.issued2022-12
dc.description.abstractABSTRACT Introduction: Hydrocephalus occurs in up to 80% of children with tuberculous meningitis (TBM), of which the majority (70-80%) is of a communicating nature. Communicating hydrocephalus develops when cerebrospinal fluid (CSF) obstruction occurs at the level of the tentorium, whilst non-communicating hydrocephalus emanates from basal exudates that obstruct the outflow foramina of the fourth ventricle. Identifying the type of hydrocephalus is of critical importance since communicating hydrocephalus can be medically treated with diuretics whilst non-communicating hydrocephalus requires surgical CSF diversion. Conventional neuroimaging does not allow differentiation of the type of hydrocephalus. In resource-limited settings, air-encephalography is the only investigative modality that allows differentiation. en_ZA
dc.identifier.urihttp://hdl.handle.net/10019.1/126389
dc.language.isoen_ZAen_ZA
dc.subjecttuberculous meningitisen_ZA
dc.subjectchildhooden_ZA
dc.subjecthydrocephalusen_ZA
dc.titleClinical determinants distinguishing communicating and non-communicating hydrocephalus in childhood tuberculous meningitis at presentationen_ZA
dc.typeThesisen_ZA
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