The Cameroon Mobile Phone SMS (CAMPS) trial : a protocol for a randomized controlled trial of mobile phone text messaging versus usual care for improving adherence to highly active anti-retroviral therapy

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dc.contributor.authorMbuagbaw, Lawrence
dc.contributor.authorThabane, Lahana
dc.contributor.authorOngolo-Zogo, Pierre
dc.contributor.authorLester, Richard T.
dc.contributor.authorMills, Edward
dc.contributor.authorVolmink, Jimmy
dc.contributor.authorYondo, David
dc.contributor.authorEssi, Marie Jose
dc.contributor.authorBonono-Momnougui, Renee-Cecile
dc.contributor.authorMba, Robert
dc.contributor.authorNdongo, Jean Serge
dc.contributor.authorNkoa, Francois C.
dc.contributor.authorOndoa, Henri Atangana
dc.date.accessioned2014-02-07T13:53:26Z
dc.date.available2014-02-07T13:53:26Z
dc.date.issued2011-01
dc.date.updated2013-12-03T10:47:07Z
dc.descriptionPlease cite as follows:en_ZA
dc.descriptionMbuagbaw, L. et al. 2011. The Cameroon Mobile Phone SMS (CAMPS) trial: a protocol for a randomized controlled trial of mobile phone text messaging versus usual care for improving adherence to highly active anti-retroviral therapy. Trials, 12(1):5, doi:10.1186/1745-6215-12-5.
dc.descriptionThe original publication is available at http://www.trialsjournal.com/content/12/1/5
dc.description.abstractBackground: This trial aims at testing the efficacy of weekly reminder and motivational text messages, compared to usual care in improving adherence to Highly Active Antiretroviral Treatment in patients attending a clinic in Yaoundé, Cameroon. Methods and Design: This is a single-centered randomized controlled single-blinded trial. A central computer generated randomization list will be generated using random block sizes. Allocation will be determined by sequentially numbered sealed opaque envelopes. 198 participants will either receive the mobile phone text message or usual care. Our hypothesis is that weekly motivational text messages can improve adherence to Highly Active Antiretroviral Treatment and other clinical outcomes in the control group by acting as a reminder, a cue to action and opening communication channels. Data will be collected at baseline, three months and six months. A blinded program secretary will send out text messages and record delivery. Our primary outcomes are adherence measured by the visual analogue scale, self report, and pharmacy refill data. Our secondary outcomes are clinical: weight, body mass index, opportunistic infections, all cause mortality and retention; biological: Cluster Designation 4 count and viral load; and quality of life. Analysis will be by intention-to-treat. Covariates and subgroups will be taken into account. Discussion: This trial investigates the potential of SMS motivational reminders to improve adherence to Highly Active Antiretroviral Treatment in Cameroon. The intervention targets non-adherence due to forgetfulness and other forms of non-adherence. Trial Registration: Pan-African Clinical Trials Registry PACTR201011000261458 http://clinicaltrials.gov/ NCT01247181en_ZA
dc.description.versionPublishers' Versionen_ZA
dc.format.extent8 p.
dc.identifier.citationMbuagbaw, L. et al. 2011. The Cameroon Mobile Phone SMS (CAMPS) trial: a protocol for a randomized controlled trial of mobile phone text messaging versus usual care for improving adherence to highly active anti-retroviral therapy. Trials, 12(1):5, doi:10.1186/1745-6215-12-5.en_ZA
dc.identifier.issn1745-6215 (online)
dc.identifier.otherdoi:10.1186/1745-6215-12-5
dc.identifier.urihttp://hdl.handle.net/10019.1/86129
dc.language.isoen_ZAen_ZA
dc.publisherBioMed Centralen_ZA
dc.rights.holderLawrence Mbuagbaw et al.; licensee BioMed Central Ltd.en_ZA
dc.subjectAnti-retroviral therapyen_ZA
dc.subjectHIV infections -- Chemotherapyen_ZA
dc.subjectAntiviral agentsen_ZA
dc.subjectAIDS (Disease) -- Therapyen_ZA
dc.titleThe Cameroon Mobile Phone SMS (CAMPS) trial : a protocol for a randomized controlled trial of mobile phone text messaging versus usual care for improving adherence to highly active anti-retroviral therapyen_ZA
dc.typeArticleen_ZA
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