Child with tuberculous meningitis and COVID-19 coinfection complicated by extensive cerebral sinus venous thrombosis

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dc.contributor.authorEssajee, Faridaen_ZA
dc.contributor.authorSolomons, Reganen_ZA
dc.contributor.authorGoussard, Pierreen_ZA
dc.contributor.authorVan Toorn, Ronalden_ZA
dc.date.accessioned2022-05-03T13:18:51Zen_ZA
dc.date.available2022-05-03T13:18:51Zen_ZA
dc.date.issued2020en_ZA
dc.descriptionCITATION: Essajee Farida et al. 2020. Child with tuberculous meningitis and COVID-19 coinfection complicated by extensive cerebral sinus venous thrombosis. BMJ Case Reports, 2020:13, doi:10.1136/bcr-2020-238597.en_ZA
dc.descriptionThe original publication is available at: https://casereports.bmj.comen_ZA
dc.description.abstractWe herein report a case of a child with tuberculous meningitis and COVID-19 coinfection complicated by hydrocephalus, arterial ischaemic stroke and extensive cerebral sinus venous thrombosis. Both conditions induce a proinflammatory cytokine drive resulting, among others, in a prothrombotic state. The disruption of the coagulation system in this case was supported by elevated D-dimers, fibrinogen and ferritin levels, consistent with thrombotic complications reported in some adult patients infected with COVID-19. The child also exhibited prolonged viral shedding that suggests severe disease.en_ZA
dc.description.versionPublisher's versionen_ZA
dc.format.extent3 pagesen_ZA
dc.identifier.citationEssajee Farida et al. 2020. Child with tuberculous meningitis and COVID-19 coinfection complicated by extensive cerebral sinus venous thrombosis. BMJ Case Reports, 2020:13, doi:10.1136/bcr-2020-238597en_ZA
dc.identifier.otherdoi:10.1136/bcr-2020-238597en_ZA
dc.identifier.urihttp://hdl.handle.net/10019.1/125178en_ZA
dc.language.isoen_ZAen_ZA
dc.publisherBMJ Publishing Groupen_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectMeninges -- Tuberculosisen_ZA
dc.subjectCOVID-19 (Disease)en_ZA
dc.subjectTuberculosis in childrenen_ZA
dc.subjectCerebral sinus venous thrombosisen_ZA
dc.titleChild with tuberculous meningitis and COVID-19 coinfection complicated by extensive cerebral sinus venous thrombosisen_ZA
dc.typeArticleen_ZA
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