Cognitive-perceptual deficits and symptom correlates in first-episode schizophrenia

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dc.contributor.authorOlivier, Riaan M.en_ZA
dc.contributor.authorKilian, Sanjaen_ZA
dc.contributor.authorChiliza, Bonginkosien_ZA
dc.contributor.authorAsmal, Lailaen_ZA
dc.contributor.authorOosthuizen, Petrus P.en_ZA
dc.contributor.authorEmsley, Robin A.en_ZA
dc.contributor.authorKidd, Martinen_ZA
dc.date.accessioned2018-12-12T08:02:55Z
dc.date.available2018-12-12T08:02:55Z
dc.date.issued2017
dc.descriptionCITATION: Olivier, R. M., et al. 2017. Cognitive-perceptual deficits and symptom correlates in first-episode schizophrenia. South African Journal of Psychiatry, 23:1-6, doi:10.4102/sajpsychiatry.v23i0.1049.
dc.descriptionThe original publication is available at http://www.sajp.org.za
dc.description.abstractBackground: Thought disorder and visual-perceptual deficits have been well documented, but their relationships with clinical symptoms and cognitive function remain unclear. Cognitive-perceptual deficits may underscore clinical symptoms in schizophrenia patients. Aim: This study aimed to explore how thought disorder and form perception are related with clinical symptoms and cognitive dysfunction in first-episode schizophrenia. Setting: Forty-two patients with a first-episode of schizophrenia, schizophreniform or schizoaffective disorder were recruited from community clinics and state hospitals in the Cape Town area. Methods: Patients were assessed at baseline with the Rorschach Perceptual Thinking Index (PTI), the Positive and Negative Syndrome Scale (PANSS) and the MATRICS Cognitive Consensus Battery (MCCB). Spearman correlational analyses were conducted to investigate relationships between PTI scores, PANSS factor analysis-derived domain scores and MCCB composite and subscale scores. Multiple regression models explored these relationships further. Results: Unexpectedly, poor form perception (X- %) was inversely correlated with the severity of PANSS positive symptoms (r = -0.42, p = 0.02). Good form perception (XA%) correlated significantly with speed of processing (r = 0.59, p < 0.01), working memory (r = 0.48, p < 0.01) and visual learning (r = 0.55, p < 0.01). PTI measures of thought disorder did not correlate significantly with PANSS symptom scores or cognitive performance. Conclusions: Form perception is associated with positive symptoms and impairment in executive function during acute psychosis. These findings suggest that there may be clinical value in including sensory-perceptual processing tasks in cognitive remediation and social cognitive training programmes for schizophrenia patients.en_ZA
dc.description.urihttps://sajp.org.za/index.php/sajp/article/view/1049
dc.description.versionPublisher's version
dc.format.extent6 pages
dc.identifier.citationOlivier, R. M., et al. 2017. Cognitive-perceptual deficits and symptom correlates in first-episode schizophrenia. South African Journal of Psychiatry, 23:1-6, doi:10.4102/sajpsychiatry.v23i0.1049
dc.identifier.issn2078-6786 (online)
dc.identifier.issn1608-9685 (print)
dc.identifier.otherdoi:10.4102/sajpsychiatry.v23i0.1049
dc.identifier.urihttp://hdl.handle.net/10019.1/105261
dc.language.isoen_ZAen_ZA
dc.publisherAOSIS Publishing
dc.rights.holderAuthors retain copyright
dc.subjectSchizophrenia -- Diagnosisen_ZA
dc.subjectPerceptual disordersen_ZA
dc.titleCognitive-perceptual deficits and symptom correlates in first-episode schizophreniaen_ZA
dc.typeArticleen_ZA
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