The current aetiology of malignant pleural effusion in the Western Cape Province, South Africa

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dc.contributor.authorKoegelenberg, C. F. N.en_ZA
dc.contributor.authorBennji, S. M.en_ZA
dc.contributor.authorBoer, E.en_ZA
dc.contributor.authorSchubert, P. T.en_ZA
dc.contributor.authorShaw, J. A.en_ZA
dc.contributor.authorAllwood, Brian W.en_ZA
dc.contributor.authorIrusen, E. M.en_ZA
dc.date.accessioned2019-10-01T12:29:23Z
dc.date.available2019-10-01T12:29:23Z
dc.date.issued2018-04
dc.descriptionCITATION: Koegelenberg, C. F. N. et al. 2018. The current aetiology of malignant pleural effusion in the Western Cape Province, South Africa. South African Medical Journal, 108(4):275-277, doi:10.7196/SAMJ.2018.v108i4.12914.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractBackground: Malignant pleural effusion (MPE) represents a very common cause of pleural exudates, and is one of the most challenging pleural disorders to manage. This could be attributed to the paucity of high-quality experimental evidence, and inconsistent practice worldwide. South Africa (SA) currently has no data regarding the aetiology of MPE. Objectives: To identify the most common malignancies causing MPE in a population served by a large tertiary hospital in SA, and specifically the relative contribution of mesothelioma. A secondary objective was to evaluate the efficacy of chemical pleurodesis in a subset of patients. Methods: We retrospectively included all known cases of MPE evaluated at our institution over a 3-year period with a tissue diagnosis of MPE. Results: The most common causes of MPE in a total of 274 patients were lung cancer (n=174, 63.5%), breast cancer (n=32, 11.7%), unknown primary (n=22, 11.7%) and mesothelioma (n=27, 9.9%). Talc pleurodesis was performed in 81 of 194 patients (41.8%) referred to our division, and was radiologically successful in 22 of 25 (88.0%) followed up to 3 months. Conclusions: The main cause of MPE in our setting was lung cancer, followed by breast cancer, unknown primary and mesothelioma. Chemical pleurodesis was a viable palliative measure for MPE in this population.en_ZA
dc.description.urihttp://www.samj.org.za/index.php/samj/article/view/12262
dc.description.versionPublisher's version
dc.format.extent3 pagesen_ZA
dc.identifier.citationKoegelenberg, C. F. N. et al. 2018. The current aetiology of malignant pleural effusion in the Western Cape Province, South Africa. South African Medical Journal, 108(4):275-277, doi:10.7196/SAMJ.2018.v108i4.12914.
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.otherdoi:10.7196/SAMJ.2018.v108i4.12914
dc.identifier.urihttp://hdl.handle.net/10019.1/106551
dc.language.isoen_ZAen_ZA
dc.publisherHealth & Medical Publishing Groupen_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectPleural effusionsen_ZA
dc.subjectLung canceren_ZA
dc.subjectMesotheliomaen_ZA
dc.subjectMalignant tumorsen_ZA
dc.titleThe current aetiology of malignant pleural effusion in the Western Cape Province, South Africaen_ZA
dc.typeArticleen_ZA
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