Xylocaine® 10% pump spray as topical anaesthetic for venepuncture pain
| dc.contributor.author | Van Straten, A. | en_ZA |
| dc.contributor.author | Murray, A. A. | en_ZA |
| dc.contributor.author | Levin, A. I. | en_ZA |
| dc.date.accessioned | 2020-02-25T14:11:55Z | |
| dc.date.available | 2020-02-25T14:11:55Z | |
| dc.date.issued | 2018 | |
| dc.description | CITATION: Van Straten, A., Murray, A. A. & Levin, A. I. 2018. Xylocaine® 10% pump spray as topical anaesthetic for venepuncture pain. Southern African Journal of Anaesthesia and Analgesia, 24(3):75-78, doi:10.1080/22201181.2018.1450200. | |
| dc.description | The original publication is available at https://www.tandfonline.com | |
| dc.description.abstract | Background: Cutaneous analgesia for venepuncture pain can be achieved using various topically applied local anaesthetic formulations. Xylocaine® 10% Pump Spray containing lignocaine hydrochloride and 95% ethanol is exclusively recommended for mucosal anaesthesia. However, this formulation is readily able to penetrate skin. This study investigated whether topical pre-treatment with Xylocaine® 10% Pump Spray could facilitate analgesia for venepuncture. Methods: A single-centre, prospective, randomised, double-blind placebo-controlled trial was conducted. One hundred patients were enrolled. The control and intervention groups had 0.5 ml saline and 0.5 ml Xylocaine® applied for 20 min to preselected venepuncture sites. Pain associated with an 18-gauge cannula venepuncture was rated on an 11-point Numerical Rating Scale. A two-point or 30% reduction in pain would be deemed clinically significant. Results: Pain scores were lower (p = 0.001) in the Xylocaine® (median 2; 95% CI 2–3) than the saline (median 4; 95% CI 3–5) group. Moderate-to-severe pain occurred in fewer Xylocaine® (18%) than saline (42%) treated patients (relative risk 0.43, CI 0.22 to 0.48; NNT = 5). Conclusion: Topical Xylocaine® 10% Pump Spray pre-treatment provided a time-effective method of reducing venepuncture-associated pain. | en_ZA |
| dc.description.uri | https://www.tandfonline.com/doi/full/10.1080/22201181.2018.1450200 | |
| dc.description.version | Publisher's version | |
| dc.format.extent | 5 pages | |
| dc.identifier.citation | Van Straten, A., Murray, A. A. & Levin, A. I. 2018. Xylocaine® 10% pump spray as topical anaesthetic for venepuncture pain. Southern African Journal of Anaesthesia and Analgesia, 24(3):75-78, doi:10.1080/22201181.2018.1450200 | |
| dc.identifier.issn | 2220-1173 (online) | |
| dc.identifier.issn | 2220-1181 (print) | |
| dc.identifier.other | doi:10.1080/22201181.2018.1450200 | |
| dc.identifier.uri | http://hdl.handle.net/10019.1/107539 | |
| dc.language.iso | en_ZA | en_ZA |
| dc.publisher | Taylor & Francis Group | |
| dc.rights.holder | Authors retain copyright | |
| dc.subject | Local anaesthesia | en_ZA |
| dc.subject | Veins -- Puncture | en_ZA |
| dc.subject | Lidocaine | en_ZA |
| dc.subject | Analgesia | en_ZA |
| dc.title | Xylocaine® 10% pump spray as topical anaesthetic for venepuncture pain | en_ZA |
| dc.type | Article | en_ZA |