The effect of ventilatory patterns on prostacyclin (PGI2) synthesis in the lung

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dc.contributor.authorDu Toit, H. J.en_ZA
dc.contributor.authorErasmus, F. R.en_ZA
dc.contributor.authorMacfarlane, C. M.en_ZA
dc.contributor.authorTaljaard, J. F.en_ZA
dc.contributor.authorShephard, E. G.en_ZA
dc.contributor.authorKing, J. B.en_ZA
dc.contributor.authorDe Klerk, A. J.en_ZA
dc.date.accessioned2011-03-18T14:57:39Z
dc.date.available2011-03-18T14:57:39Z
dc.date.issued1984
dc.descriptionCITATION: Du Toit, H. J. et al. 1984. The effect of ventilatory patterns on prostacyclin (PGI2) synthesis in the lung. South African Medical Journal, 65:135-136.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractProstacyclin (PGI2) appears to be synthesized in the lungs of man and experimental animals. It has been stated that PGI2 must be regarded as a local hormone that inhibits platelet adhesion to vessel walls only very close to the site of synthesis. The wide range of normal values given for PGI2 may be related to the sensitivity and exclusiveness of the different assay techniques used. In animals, hyperventilation increases PGI2 synthesis by the lung, but in agreement with other authors we demonstrated that hyperventilation did not influence PGI2 synthesis in man. We used a radio-immunoassay technique to estimate PGI2 levels.
dc.description.versionPublisher’s version
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/7558
dc.language.isoen
dc.publisherHealth & Medical Publishing Group
dc.rights.holderSouth African Medical Journal
dc.subjectLungsen_ZA
dc.titleThe effect of ventilatory patterns on prostacyclin (PGI2) synthesis in the lungen_ZA
dc.typeArticle
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