The clinical value of ERCP-guided cholangiopancreatoscopy using a singleoperator system

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dc.contributor.authorReuterwall, Marcusen_ZA
dc.contributor.authorLubbe, Jeanneen_ZA
dc.contributor.authorEnochsson, Larsen_ZA
dc.contributor.authorLundell, Larsen_ZA
dc.contributor.authorKonradsson, Magnusen_ZA
dc.contributor.authorSwahn, Frederiken_ZA
dc.contributor.authorDel Chiaro, Marcoen_ZA
dc.contributor.authorLohr, Matthiasen_ZA
dc.contributor.authorArnelo, Urbanen_ZA
dc.date.accessioned2021-06-25T09:03:51Z
dc.date.available2021-06-25T09:03:51Z
dc.date.issued2019
dc.descriptionCITATION: Reuterwall, M. et al. 2019. The clinical value of ERCP-guided cholangiopancreatoscopy using a singleoperator system. BMC Gastroenterology, 19:35, doi:10.1186/s12876-019-0953-9.
dc.descriptionThe original publication is available at https://bmcgastroenterol.biomedcentral.com
dc.description.abstractBackground: Single-operator, per-oral cholangiopancreatoscopy (SOPCP) enables direct biliopancreatic ductal visualization, targeted tissue sampling, and therapeutic intervention. At Karolinska University Hospital, SOPCP was introduced early and has since been extensively utilized according to a standardized protocol. We analysed the clinical value of SOPCP in the diagnosis and treatment of biliopancreatic diseases in a single high volume center. Methods: All SOPCP procedures performed between March 2007 and December 2014 were retrospectively reviewed. Each procedure’s diagnostic yield and therapeutic value was evaluated using a predefined 4 grade scale; 1 - no diagnostic or therapeutic value, 2 - information gained did not impact clinical decision-making and in case of a therapeutic intervention, did not alter the clinical course of the patient, 3 - information gained had an impact on clinical decision-making and in the case of a therapeutic intervention, assisted subsequent disease management, and finally, 4 - information gained was essential and critical for clinical decision-making and in case of a therapeutic intervention, solved the clinical problem requiring no further therapeutic actions. Descriptive statistics were used to analyse results, with uni- and multivariate analyses completed to assess risk of adverse events. Results: During the study period, 365 SOPCP procedures were performed. We found SOPCP of pivotal importance (grade 4) in 19% of cases, and of great clinical significance (grade 3) in 44% of cases. SOPCP did not affect clinical decision-making or alter clinical course (grade 1 and 2) in 37% of cases. Conclusion: SOPCP offers direct access to the biliopancreatic ducts for both diagnostic and therapeutic purposes, adding significant clinical value in 64% of cases.en_ZA
dc.description.urihttps://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-019-0953-9
dc.description.versionPublisher's version
dc.format.extent7 pagesen_ZA
dc.identifier.citationReuterwall, M. et al. 2019. The clinical value of ERCP-guided cholangiopancreatoscopy using a singleoperator system. BMC Gastroenterology, 19:35, doi:10.1186/s12876-019-0953-9.
dc.identifier.issn1471-230X (online)
dc.identifier.otherdoi:10.1186/s12876-019-0953-9
dc.identifier.urihttp://hdl.handle.net/10019.1/110614
dc.language.isoen_ZAen_ZA
dc.publisherBioMed Centralen_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectCholangiopancreatoscopyen_ZA
dc.subjectPancreatic ducten_ZA
dc.subjectBile ductsen_ZA
dc.subjectBile ducts -- Examinationen_ZA
dc.subjectBile ducts -- Surgeryen_ZA
dc.titleThe clinical value of ERCP-guided cholangiopancreatoscopy using a singleoperator systemen_ZA
dc.typeArticleen_ZA
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