Familial-environmental risk factors in South African children with ADHD : a case-control study

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dc.contributor.advisorVan Toorn, Ronalden_ZA
dc.contributor.advisorSpringer, Priscillaen_ZA
dc.contributor.authorVan Dyk, Leanaen_ZA
dc.contributor.otherPaediatrics and Child Healthen_ZA
dc.date.accessioned2016-12-22T14:44:35Z
dc.date.available2016-12-22T14:44:35Z
dc.date.issued2016-06-16
dc.descriptionCITATION: Van Dyk, L. et al. 2015. Familial-Environmental Risk Factors in South African Children With Attention-Deficit Hyperactivity Disorder (ADHD): A Case-Control Study. Journal of Child Neurology, 30(10):1327–1332, doi:10.1177/0883073814560630.en_ZA
dc.descriptionThe original publication is available at https://journals.sagepub.com/home/jcnen_ZA
dc.description.abstractWe investigated familial and environmental risk factors in a cohort of South African children diagnosed with attention-deficit hyperactivity disorder (ADHD). A prospective, hospital-based case control study was conducted comprising 50 children diagnosed with ADHD and 50 matched non-ADHD controls. The adjusted effect of familial-environmental risk factors on ADHD was determined by systematic assessment. Birth complications, parental psychiatric disorder, maternal ADHD, early childhood trauma, and nonmaternal child care were significant risk factors for ADHD. Prolonged breastfeeding was found to be protective. In a multivariable logistic regression model, 5 criteria (birth complications, breastfeeding <3 months, at least 1 parent with tertiary education, presence of parental psychiatric disorder, and nonmaternal primary caregiver) differentiated ADHD from non-ADHD controls with a sensitivity and specificity of 74% and 86%, respectively. We found a correlation between certain familial and environmental risk factors and ADHD. A 5-criterion multivariable logistic regression model may offer clinical guidance in ADHD diagnosis.en_ZA
dc.description.versionPre-printen_ZA
dc.identifier.citationVan Dyk, L. et al. 2015. Familial-Environmental Risk Factors in South African Children With Attention-Deficit Hyperactivity Disorder (ADHD): A Case-Control Study. Journal of Child Neurology, 30(10):1327–1332, doi:10.1177/0883073814560630.en_ZA
dc.identifier.issn1708-8283 (online)
dc.identifier.issn0883-0738 (print)
dc.identifier.otherdoi:10.1177/0883073814560630
dc.identifier.urihttp://hdl.handle.net/10019.1/100451
dc.language.isoen_ZAen_ZA
dc.publisherSage Publicationsen_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectfamilial-environmental risk factorsen_ZA
dc.subjectresource-constrained bodyen_ZA
dc.subjectADHDen_ZA
dc.subjectAttention deficit hyperactivity disorderen_ZA
dc.titleFamilial-environmental risk factors in South African children with ADHD : a case-control studyen_ZA
dc.typeArticleen_ZA
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