Diffusion markers of dendritic density and arborization in gray matter predict differences in intelligence

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dc.contributor.authorGenc, Erhanen_ZA
dc.contributor.authorFraenz, Christophen_ZA
dc.contributor.authorSchluter, Carolineen_ZA
dc.contributor.authorFriedrich, Patricken_ZA
dc.contributor.authorHossiep, Rudigeren_ZA
dc.contributor.authorVoelkle, Manuel C.en_ZA
dc.contributor.authorLing, Josef M.en_ZA
dc.contributor.authorGunturkun, Onuren_ZA
dc.contributor.authorJung, Rex E.en_ZA
dc.date.accessioned2019-10-18T13:11:17Z
dc.date.available2019-10-18T13:11:17Z
dc.date.issued2018
dc.descriptionCITATION: Genc, E., et al. 2018. Diffusion markers of dendritic density and arborization in gray matter predict differences in intelligence. Nature Communications, 9:1905, doi:10.1038/s41467-018-04268-8.
dc.descriptionThe original publication is available at https://www.nature.com
dc.description.abstractPrevious research has demonstrated that individuals with higher intelligence are more likely to have larger gray matter volume in brain areas predominantly located in parieto-frontal regions. These findings were usually interpreted to mean that individuals with more cortical brain volume possess more neurons and thus exhibit more computational capacity during reasoning. In addition, neuroimaging studies have shown that intelligent individuals, despite their larger brains, tend to exhibit lower rates of brain activity during reasoning. However, the microstructural architecture underlying both observations remains unclear. By combining advanced multi-shell diffusion tensor imaging with a culture-fair matrix-reasoning test, we found that higher intelligence in healthy individuals is related to lower values of dendritic density and arborization. These results suggest that the neuronal circuitry associated with higher intelligence is organized in a sparse and efficient manner, fostering more directed information processing and less cortical activity during reasoning.en_ZA
dc.description.urihttps://www.nature.com/articles/s41467-018-04268-8?
dc.description.versionPublisher's version
dc.format.extent11 pages
dc.identifier.citationGenc, E., et al. 2018. Diffusion markers of dendritic density and arborization in gray matter predict differences in intelligence. Nature Communications, 9:1905, doi:10.1038/s41467-018-04268-8
dc.identifier.issn2041-1723 (online)
dc.identifier.otherdoi:10.1038/s41467-018-04268-8
dc.identifier.urihttp://hdl.handle.net/10019.1/106670
dc.language.isoen_ZAen_ZA
dc.publisherNature Research (part of Springer Nature)
dc.rights.holderAuthors retain copyright
dc.subjectIntelligence levelsen_ZA
dc.subjectBrain -- Sizeen_ZA
dc.subjectNeural circuitryen_ZA
dc.subjectHigher nervous activityen_ZA
dc.subjectPeriaqueductal gray matteren_ZA
dc.titleDiffusion markers of dendritic density and arborization in gray matter predict differences in intelligenceen_ZA
dc.typeArticleen_ZA
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