Arterial oxygenation and one-lung anesthesia

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dc.contributor.authorLevin A.I.
dc.contributor.authorCoetzee J.F.
dc.contributor.authorCoetzee A.
dc.date.accessioned2011-05-15T16:16:11Z
dc.date.available2011-05-15T16:16:11Z
dc.date.issued2008
dc.description.abstractPURPOSE OF REVIEW: In the presence of the obligatory shunt during one-lung ventilation, arterial oxygenation is determined by the magnitude of the shunt in addition to the oxygen content of the mixed venous blood coursing through that shunt. The present discussion aims to heighten awareness of factors determining arterial oxygenation during one-lung anesthesia, other than the magnitude of the shunt and dependent lung low-ventilation perfusion units. RECENT FINDINGS: A convenient way to increase mixed venous and thereby arterial oxygenation is to raise cardiac output. While this approach has achieved some success when increasing cardiac output from low levels, other studies have highlighted limitations of this approach when cardiac output attains very high levels. The effect of anesthesia techniques on the relationship between oxygen consumption and cardiac output could also explain unanswered questions regarding the pathophysiology of arterial oxygenation during one-lung anesthesia. SUMMARY: The effects of anesthesia techniques on oxygen consumption, cardiac output and therefore mixed venous oxygenation can significantly affect arterial oxygenation during one-lung anesthesia. While pursuing increases in cardiac output may, under limited circumstances, benefit arterial oxygenation during one-lung ventilation, this approach is not a panacea and does not obviate the necessity to optimize dependent lung volume. © 2008 Lippincott Williams & Wilkins, Inc.
dc.description.versionReview
dc.identifier.citationCurrent Opinion in Anaesthesiology
dc.identifier.citation21
dc.identifier.citation1
dc.identifier.issn09527907
dc.identifier.other10.1097/ACO.0b013e3282f2bb79
dc.identifier.urihttp://hdl.handle.net/10019.1/13671
dc.subjectanesthesiological techniques
dc.subjectarterial oxygen saturation
dc.subjectendobronchial anesthesia
dc.subjectheart output
dc.subjectheart right left shunt
dc.subjecthuman
dc.subjectlung perfusion
dc.subjectlung ventilation
dc.subjectlung volume
dc.subjectnonhuman
dc.subjectoxygen consumption
dc.subjectpositive end expiratory pressure
dc.subjectpriority journal
dc.subjectreview
dc.subjectvenous oxygen tension
dc.subjectAnesthesia
dc.subjectCardiac Output
dc.subjectHemoglobins
dc.subjectHumans
dc.subjectOxygen
dc.subjectOxygen Consumption
dc.titleArterial oxygenation and one-lung anesthesia
dc.typeReview
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