Progressive familial heart block, two types
| dc.contributor.author | Brink A. J. | en_ZA |
| dc.contributor.author | Torrington, M. | en_ZA |
| dc.date.accessioned | 2011-03-18T14:57:51Z | |
| dc.date.available | 2011-03-18T14:57:51Z | |
| dc.date.issued | 1977 | |
| dc.description | CITATION: Brink A. J. & Torrington, M. 1977. Progressive familial heart block, two types. South African Medical Journal, 52(2):53-59. | |
| dc.description | The original publication is available at http://www.samj.org.za | |
| dc.description.abstract | Two types of heart block which occur extensively in families in the Republic of South Africa are reported. A type I heart block tends to have the pattern of a right bundle-branch block and/or left anterior hemiblock occurring individually or together, and manifested clinically when complete heart block supervenes, either with syncopal episodes, Stokes-Adams seizures or sudden death. The condition is inherited r356w1++3.3.1 as an autosomal dominant gene and appears to be progressive in nature; the risk to life appears to be greatest at 3 particular periods: at or soon after birth, during puberty and the early 20s, and again towards middle age. The type II condition also appears to be progressive and is inherited as an autosomal dominant gene. The pattern, however, tends to develop along the lines of a sinus bradycardia with a left posterior hemiblock, again presenting clinically as syncopal episodes, Stokes-Adams seizures or sudden death when complete heart block supervenes. Both conditions are likely to be widely prevalent throughout the Republic of South Africa. The pathogenesis is discussed in relation to the patterns of the conduction disturbances. | |
| dc.description.version | Publisher’s version | |
| dc.identifier.citation | Brink A. J. & Torrington, M. 1977. Progressive familial heart block, two types. South African Medical Journal, 52(2):53-59 | |
| dc.identifier.issn | 2078-5135 (online) | |
| dc.identifier.issn | 0256-9574 (print) | |
| dc.identifier.uri | http://hdl.handle.net/10019.1/7697 | |
| dc.language.iso | en | en_ZA |
| dc.publisher | Health & Medical Publishing Group | |
| dc.rights.holder | South African Medical Journal | |
| dc.subject | Heart block | |
| dc.title | Progressive familial heart block, two types | en_ZA |
| dc.type | Article |
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