Mobile phone radiation does not induce pro-apoptosis effects in human Spermatozoa

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dc.contributor.authorFalzone N.
dc.contributor.authorHuyser C.
dc.contributor.authorFranken D.R.
dc.contributor.authorLeszczynski D.
dc.date.accessioned2011-05-15T16:17:48Z
dc.date.available2011-05-15T16:17:48Z
dc.date.issued2010
dc.description.abstractRecent reports suggest that mobile phone radiation may diminish male fertility. However, the effects of this radiation on human spermatozoa are largely unknown. The present study examined effects of the radiation on induction of apoptosis-related properties in human spermatozoa. Ejaculated, density-purified, highly motile human spermatozoa were exposed to mobile phone radiation at specific absorption rates (SARs) of 2.0 and 5.7 W/kg. At various times after exposure, flow cytometry was used to examine caspase 3 activity, externalization of phosphatidylserine (PS), induction of DNA strand breaks, and generation of reactive oxygen species. Mobile phone radiation had no statistically significant effect on any of the parameters studied. This suggests that the impairment of fertility reported in some studies was not caused by the induction of apoptosis in spermatozoa. © 2010 by Radiation Research Society.
dc.description.versionArticle
dc.identifier.citationRadiation Research
dc.identifier.citation174
dc.identifier.citation2
dc.identifier.issn00337587
dc.identifier.other10.1667/RR2091.1
dc.identifier.urihttp://hdl.handle.net/10019.1/14375
dc.subjectcaspase 3
dc.subjectlipocortin 5
dc.subjectphosphatidylserine
dc.subjectreactive oxygen metabolite
dc.subjectapoptosis
dc.subjectarticle
dc.subjectDNA fragmentation
dc.subjectDNA strand breakage
dc.subjectenzyme activation
dc.subjectenzyme activity
dc.subjectflow cytometry
dc.subjecthuman
dc.subjectmale
dc.subjectmobile phone
dc.subjectnormal human
dc.subjectpriority journal
dc.subjectradiation exposure
dc.subjectspermatozoon motility
dc.subjectApoptosis
dc.subjectCaspase 3
dc.subjectCaspases
dc.subjectCellular Phone
dc.subjectFertility
dc.subjectHumans
dc.subjectInfertility, Male
dc.subjectMale
dc.subjectOxidative Stress
dc.subjectPaternal Exposure
dc.subjectSpermatozoa
dc.titleMobile phone radiation does not induce pro-apoptosis effects in human Spermatozoa
dc.typeArticle
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