Hypodipsic-hypernatremia syndrome in an adult with polycythemia : a case report

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dc.contributor.authorChothia, Mogamat-Yazieden_ZA
dc.contributor.authorGeorge, Kiranen_ZA
dc.contributor.authorSheik, Muhammeden_ZA
dc.contributor.authorDavids, Mogamat Razeenen_ZA
dc.date.accessioned2019-01-15T13:41:23Z
dc.date.available2019-01-15T13:41:23Z
dc.date.issued2018-12-27
dc.date.updated2019-01-15T11:49:50Z
dc.descriptionCITATION: Chothia, M. Y., et al. 2019. Hypodipsic-hypernatremia syndrome in an adult with polycythemia : a case report. Journal of Medical Case Reports, 12:381, doi:10.1186/s13256-018-1938-y.
dc.descriptionThe original publication is available at https://jmedicalcasereports.biomedcentral.com
dc.description.abstractBackground: Hypernatremia is a very common electrolyte disorder and is frequently encountered in out-patient as well as in-hospital settings. We describe an adult who was found to have unexplained relative polycythemia and episodic hypernatremia. A diagnosis of idiopathic hypodipsic-hypernatremia syndrome was made and the patient was managed with a water-drinking schedule. Case presentation: A 24-year-old South African-Indian man was found to have polycythemia in association with episodes of hypernatremia. Investigations indicated that he had relative polycythemia. He experienced no thirst at a time when his serum sodium concentration was found to be 151 mmol/L. Further testing indicated that his renal response to arginine vasopressin was intact and magnetic resonance imaging of his brain revealed no hypothalamic lesions. A diagnosis of idiopathic hypodipsic-hypernatremia syndrome was made and he was managed with a water-drinking schedule that corrected his hypernatremia. Conclusion: Hypodipsia should always be considered when a patient without physical or cognitive disability presents with unexplained episodic hypernatremia or with relative polycythemia.
dc.description.urihttps://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-018-1938-y
dc.description.versionPublisher's version
dc.format.extent6 pagesen_ZA
dc.identifier.citationChothia, M. Y., et al. 2019. Hypodipsic-hypernatremia syndrome in an adult with polycythemia : a case report. Journal of Medical Case Reports, 12:381, doi:10.1186/s13256-018-1938-y
dc.identifier.issn1752-1947 (online)
dc.identifier.otherdoi:10.1186/s13256-018-1938-y
dc.identifier.urihttp://hdl.handle.net/10019.1/105328
dc.language.isoen_ZAen_ZA
dc.publisherBMC (part of Springer Nature)en_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectHypernatremiaen_ZA
dc.subjectElectrolyte disorderen_ZA
dc.subjectPolycythemiaen_ZA
dc.titleHypodipsic-hypernatremia syndrome in an adult with polycythemia : a case reporten_ZA
dc.typeArticleen_ZA
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