Single dose abacavir pharmacokinetics and safety in neonates exposed to human immunodeficiency virus (HIV)

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dc.contributor.authorBekker, Adrieen_ZA
dc.contributor.authorDecloedt, Eric H.en_ZA
dc.contributor.authorSlade, Gretchenen_ZA
dc.contributor.authorCotton, Mark F.en_ZA
dc.contributor.authorRabie, Helenaen_ZA
dc.contributor.authorCressey, Tim R.en_ZA
dc.date.accessioned2022-06-06T09:18:46Zen_ZA
dc.date.available2022-06-06T09:18:46Zen_ZA
dc.date.issued2021-06en_ZA
dc.descriptionCITATION: Bekker, A. et al. 2020. Single Dose Abacavir Pharmacokinetics and Safety in Neonates Exposed to Human Immunodeficiency Virus (HIV). Clinical Infectious Diseases, 72 (11): 2032–2034. doi:10.1093/cid/ciaa1026en_ZA
dc.descriptionThe original publication is available at https://academic.oup.com/cid/en_ZA
dc.description.abstractAbacavir is a potential option for prophylaxis and early treatment of human immunodeficiency virus (HIV), but no data are available in neonates. Ten neonates administered a single abacavir dose of 8 mg/kg before 15 days of life had substantially higher exposures than those reported in infants and children, with no reported adverse events.en_ZA
dc.description.urihttps://academic.oup.com/cid/article/72/11/2032/5874909?login=trueen_ZA
dc.description.versionPublishers versionen_ZA
dc.format.extent3 pagesen_ZA
dc.identifier.citationBekker, A. et al. 2020. Single Dose Abacavir Pharmacokinetics and Safety in Neonates Exposed to Human Immunodeficiency Virus (HIV). Clinical Infectious Diseases, 72 (11): 2032–2034. doi:10.1093/cid/ciaa1026en_ZA
dc.identifier.issn1537-6591 (online)en_ZA
dc.identifier.issn1058-4838 (print)en_ZA
dc.identifier.otherdoi:10.1093/cid/ciaa1026en_ZA
dc.identifier.urihttp://hdl.handle.net/10019.1/125320en_ZA
dc.language.isoen_ZAen_ZA
dc.publisherOxford University Pressen_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectHIV infections -- Treatmenten_ZA
dc.subjectHIV (Viruses) -- Transmissionen_ZA
dc.subjectAntiretroviral agentsen_ZA
dc.subjectPharmacokineticsen_ZA
dc.subjectNeonatal intensive careen_ZA
dc.subjectPerinatal pharmacologyen_ZA
dc.titleSingle dose abacavir pharmacokinetics and safety in neonates exposed to human immunodeficiency virus (HIV)en_ZA
dc.typeArticleen_ZA
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