Association of simple renal cysts and chronic kidney disease with large abdominal aortic aneurysm

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dc.contributor.authorMiszczuk, Milenaen_ZA
dc.contributor.authorMüller, Verenaen_ZA
dc.contributor.authorAlthoff, Christian E.en_ZA
dc.contributor.authorStroux, Andreaen_ZA
dc.contributor.authorWidhalm, Danielaen_ZA
dc.contributor.authorDobberstein, Andyen_ZA
dc.contributor.authorGreiner, Andreasen_ZA
dc.contributor.authorKuivaniemi, Helenaen_ZA
dc.contributor.authorHinterseher, Ireneen_ZA
dc.date.accessioned2020-06-02T08:43:49Z
dc.date.available2020-06-02T08:43:49Z
dc.date.issued2020-05-29
dc.date.updated2020-05-31T03:18:27Z
dc.descriptionCITATION: Miszczuk, M., et. al. 2020. Association of simple renal cysts and chronic kidney disease with large abdominal aortic aneurysm. BMC Nephrology, 21:201, doi:10.1186/s12882-020-01841-6.
dc.descriptionThe original publication is available at https://bmcnephrol.biomedcentral.com
dc.description.abstractBackground: Abdominal aortic aneurysms (AAA) primarily affect men over 65 years old who often have many other diseases, with similar risk factors and pathobiological mechanisms to AAA. The aim of this study was to assess the prevalence of simple renal cysts (SRC), chronic kidney disease (CKD), and other kidney diseases (e.g. nephrolithiasis) among patients presenting with AAA. Methods: Two groups of patients (97 AAA and 100 controls), with and without AAA, from the Surgical Clinic Charité, Berlin, Germany, were selected for the study. The control group consisted of patients who were evaluated for a kidney donation (n = 14) and patients who were evaluated for an early detection of a melanoma recurrence (n = 86). The AAA and control groups were matched for age and sex. Medical records were analyzed and computed tomography scans were reviewed for the presence of SRC and nephrolithiasis. Results: SRC (74% vs. 57%; p<0.016) and CKD (30% vs. 8%; p<0.001) were both more common among AAA than control group patients. On multivariate analysis, CKD, but not SRC, showed a strong association with AAA. Conclusions: Knowledge about pathobiological mechanisms and association between CKD and AAA could provide better diagnostic and therapeutic approaches for these patients.en
dc.description.urihttps://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-020-01841-6
dc.description.urihttps://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-020-01841-6
dc.description.versionPublisher's version
dc.format.extent9 pages ; illustrations
dc.identifier.citationMiszczuk, M., et. al. 2020. Association of simple renal cysts and chronic kidney disease with large abdominal aortic aneurysm. BMC Nephrology, 21:201, doi:10.1186/s12882-020-01841-6
dc.identifier.issn1471-2369 (online)
dc.identifier.otherdoi:10.1186/s12882-020-01841-6
dc.identifier.urihttp://hdl.handle.net/10019.1/108639
dc.language.isoen_ZAen_ZA
dc.publisherBMC (part of Springer Nature)
dc.rights.holderAuthors retain copyright
dc.subjectAortic aneurysmsen_ZA
dc.subjectAbdominal aneurysmen_ZA
dc.subjectKidney, Cysticen_ZA
dc.subjectChronic renal failureen_ZA
dc.titleAssociation of simple renal cysts and chronic kidney disease with large abdominal aortic aneurysmen_ZA
dc.typeArticle
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